Gene Symbol | YLPM1 |
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Entrez Gene | 56252 |
Alt Symbol | C14orf170, PPP1R169, ZAP113, ZAP3 |
Species | Human |
Gene Type | protein-coding |
Description | YLP motif containing 1 |
Other Description | YLP motif-containing protein 1|nuclear protein ZAP3|protein phosphatase 1, regulatory subunit 169 |
Swissprots | Q96I64 Q9P1V7 P49752 P49750 |
Accessions | AAF61275 P49750 AK090435 BAC03416 AK095760 AK096592 AK297582 BAG59971 AL832365 BC007792 AAH07792 BC023570 AAH23570 BC044636 AAH44636 BC172585 AAI72585 BX102033 BX647164 DB096717 L40396 L40400 AAC42006 L40403 AAC42008 XM_005267860 XP_005267917 XM_011536966 XP_011535268 XM_011536967 XP_011535269 XR_943494 NM_019589 NP_062535 |
Function | Plays a role in the reduction of telomerase activity during differentiation of embryonic stem cells by binding to the core promoter of TERT and controlling its down-regulation. {ECO:0000250}. |
Subcellular Location | Nucleus {ECO:0000269|PubMed:17890166}. Nucleus speckle {ECO:0000250}. Note=Migrates to nucleolar caps upon blockage of transcription. |
Tissue Specificity | Expressed in neuronal, neuroblastoma and embryonic kidney cell lines (at protein level). {ECO:0000269|PubMed:17890166}. |
Zap3 CRISPR/Cas9 KO Plasmid (h) - sc-412693 from Santa Cruz Biotechnology
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Zap3 HDR Plasmid (h) - sc-412693-HDR from Santa Cruz Biotechnology
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Zap3 Double Nickase Plasmid (h) - sc-412693-NIC from Santa Cruz Biotechnology
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Zap3 Double Nickase Plasmid (h2) - sc-412693-NIC-2 from Santa Cruz Biotechnology
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Zap3 CRISPR Activation Plasmid (h) - sc-412693-ACT from Santa Cruz Biotechnology
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Zap3 CRISPR Activation Plasmid (h2) - sc-412693-ACT-2 from Santa Cruz Biotechnology
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Zap3 Lentiviral Activation Particles (h) - sc-412693-LAC from Santa Cruz Biotechnology
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Zap3 Lentiviral Activation Particles (h2) - sc-412693-LAC-2 from Santa Cruz Biotechnology
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Zap3 siRNA (h) - sc-92299 from Santa Cruz Biotechnology
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Zap3 shRNA Plasmid (h) - sc-92299-SH from Santa Cruz Biotechnology
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Zap3 shRNA (h) Lentiviral Particles - sc-92299-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU059691 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN23015 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND23015 from Sigma-Aldrich
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YLPM1 siRNA (Human) - CRJ1115 from Cohesion Biosciences
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YLPM1 - MBS8220201 from MyBioSource
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shRNA set against Human YLPM1 (NM_019589.2) - SHH448496 from Creative biogene
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shRNA set against Human YLPM1(NM_019589.2) - SHL140400 from Creative biogene
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Human YLPM1 siRNA - orb271616 from Biorbyt
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YLPM1 shRNA Plasmid (Human) - CHJ1115 from Cohesion Biosciences
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YLPM1 miRNA 3'UTR clone - MiUTR1H-11338 from Creative biogene
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