| Gene Symbol |
ZNF335
|
| Entrez Gene |
63925
|
| Alt Symbol |
MCPH10, NIF-1, NIF1, NIF2
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
zinc finger protein 335
|
| Other Description |
NRC-interacting factor 1|zinc-finger/leucine-zipper co-transducer NIF1
|
| Swissprots |
Q548D0 Q9H684 B4DLG7 Q9H4Z2
|
| Accessions |
EAW75777 Q9H4Z2 AF395833 AAN09900 AK026157 BAB15379 AK027358 AK054694 AK074214 AK092485 AK122963 AK296989 BAG59529 BC041331 AAH41331 BC142981 BC166679 AAI66679 BF755826 XM_005260504 XP_005260561 XM_005260506 XP_005260563 XM_011528979 XP_011527281 XR_936602 XR_936603 XR_936604 NM_022095 NP_071378
|
| Function |
Component or associated component of some histone methyltransferase complexes may regulate transcription through recruitment of those complexes on gene promoters. Enhances ligand- dependent transcriptional activation by nuclear hormone receptors. Plays an important role in neural progenitor cell proliferation and self-renewal through the regulation of specific genes involved brain development, including REST. Also controls the expression of genes involved in somatic development and regulates, for instance, lymphoblast proliferation. {ECO:0000269|PubMed:12215545, ECO:0000269|PubMed:18180299, ECO:0000269|PubMed:23178126}.
|
| Subcellular Location |
Nucleus {ECO:0000269|PubMed:12215545}.
|
| Tissue Specificity |
Ubiquitously expressed. {ECO:0000269|PubMed:12215545, ECO:0000269|PubMed:23178126}.
|