Gene Symbol | ZNF335 |
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Entrez Gene | 63925 |
Alt Symbol | MCPH10, NIF-1, NIF1, NIF2 |
Species | Human |
Gene Type | protein-coding |
Description | zinc finger protein 335 |
Other Description | NRC-interacting factor 1|zinc-finger/leucine-zipper co-transducer NIF1 |
Swissprots | Q548D0 Q9H684 B4DLG7 Q9H4Z2 |
Accessions | EAW75777 Q9H4Z2 AF395833 AAN09900 AK026157 BAB15379 AK027358 AK054694 AK074214 AK092485 AK122963 AK296989 BAG59529 BC041331 AAH41331 BC142981 BC166679 AAI66679 BF755826 XM_005260504 XP_005260561 XM_005260506 XP_005260563 XM_011528979 XP_011527281 XR_936602 XR_936603 XR_936604 NM_022095 NP_071378 |
Function | Component or associated component of some histone methyltransferase complexes may regulate transcription through recruitment of those complexes on gene promoters. Enhances ligand- dependent transcriptional activation by nuclear hormone receptors. Plays an important role in neural progenitor cell proliferation and self-renewal through the regulation of specific genes involved brain development, including REST. Also controls the expression of genes involved in somatic development and regulates, for instance, lymphoblast proliferation. {ECO:0000269|PubMed:12215545, ECO:0000269|PubMed:18180299, ECO:0000269|PubMed:23178126}. |
Subcellular Location | Nucleus {ECO:0000269|PubMed:12215545}. |
Tissue Specificity | Ubiquitously expressed. {ECO:0000269|PubMed:12215545, ECO:0000269|PubMed:23178126}. |
NIF-1 CRISPR/Cas9 KO Plasmid (h) - sc-412963 from Santa Cruz Biotechnology
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NIF-1 HDR Plasmid (h) - sc-412963-HDR from Santa Cruz Biotechnology
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NIF-1 Double Nickase Plasmid (h) - sc-412963-NIC from Santa Cruz Biotechnology
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NIF-1 Double Nickase Plasmid (h2) - sc-412963-NIC-2 from Santa Cruz Biotechnology
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NIF-1 CRISPR Activation Plasmid (h) - sc-412963-ACT from Santa Cruz Biotechnology
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NIF-1 CRISPR Activation Plasmid (h2) - sc-412963-ACT-2 from Santa Cruz Biotechnology
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NIF-1 Lentiviral Activation Particles (h) - sc-412963-LAC from Santa Cruz Biotechnology
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NIF-1 Lentiviral Activation Particles (h2) - sc-412963-LAC-2 from Santa Cruz Biotechnology
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NIF-1 siRNA (h) - sc-75914 from Santa Cruz Biotechnology
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NIF-1 shRNA Plasmid (h) - sc-75914-SH from Santa Cruz Biotechnology
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NIF-1 shRNA (h) Lentiviral Particles - sc-75914-V from Santa Cruz Biotechnology
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NIF1 RNAi - H00063925-R01 from Novus Biologicals
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MISSION® esiRNA - EHU079361 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN23396 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND23396 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR01707 from Sigma-Aldrich
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ZNF335 siRNA (Human) - CRJ1865 from Cohesion Biosciences
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ZNF335 - MBS8207364 from MyBioSource
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shRNA set against Human ZNF335 (NM_022095.3) - SHH453704 from Creative biogene
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Human ZNF335 siRNA - orb272366 from Biorbyt
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ZNF335 shRNA Plasmid (Human) - CHJ1865 from Cohesion Biosciences
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ZNF335 miRNA 3'UTR clone - MiUTR1H-11563 from Creative biogene
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