| Gene Symbol |
HSPA2
|
| Entrez Gene |
3306
|
| Alt Symbol |
HSP70-2, HSP70-3
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
heat shock 70kDa protein 2
|
| Other Description |
heat shock 70kD protein 2|heat shock-related 70 kDa protein 2
|
| Swissprots |
Q9UE78 Q53XM3 P54652 Q15508
|
| Accessions |
AAA52698 ABE96830 EAW80864 EAW80865 P54652 AK097824 BAG53534 BC001752 AAH01752 BC034365 BC036107 AAH36107 BG772858 BI461827 BT009815 AAP88817 CD300159 CN356507 DB042367 DQ892538 ABM83464 DQ895749 ABM86675 NM_021979 NP_068814
|
| Function |
In cooperation with other chaperones, Hsp70s stabilize preexistent proteins against aggregation and mediate the folding of newly translated polypeptides in the cytosol as well as within organelles. These chaperones participate in all these processes through their ability to recognize nonnative conformations of other proteins. They bind extended peptide segments with a net hydrophobic character exposed by polypeptides during translation and membrane translocation, or following stress-induced damage.
|
| Top Pathways |
Estrogen signaling pathway, Epstein-Barr virus infection, Legionellosis, Influenza A, Measles
|
