Gene Symbol | HSPA2 |
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Entrez Gene | 3306 |
Alt Symbol | HSP70-2, HSP70-3 |
Species | Human |
Gene Type | protein-coding |
Description | heat shock 70kDa protein 2 |
Other Description | heat shock 70kD protein 2|heat shock-related 70 kDa protein 2 |
Swissprots | Q9UE78 Q53XM3 P54652 Q15508 |
Accessions | AAA52698 ABE96830 EAW80864 EAW80865 P54652 AK097824 BAG53534 BC001752 AAH01752 BC034365 BC036107 AAH36107 BG772858 BI461827 BT009815 AAP88817 CD300159 CN356507 DB042367 DQ892538 ABM83464 DQ895749 ABM86675 NM_021979 NP_068814 |
Function | In cooperation with other chaperones, Hsp70s stabilize preexistent proteins against aggregation and mediate the folding of newly translated polypeptides in the cytosol as well as within organelles. These chaperones participate in all these processes through their ability to recognize nonnative conformations of other proteins. They bind extended peptide segments with a net hydrophobic character exposed by polypeptides during translation and membrane translocation, or following stress-induced damage. |
Top Pathways | Estrogen signaling pathway, Epstein-Barr virus infection, Legionellosis, Influenza A, Measles |
HSPA2 CRISPR/Cas9 KO Plasmid (h) - sc-400832 from Santa Cruz Biotechnology
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HSPA2 HDR Plasmid (h) - sc-400832-HDR from Santa Cruz Biotechnology
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HSPA2 Double Nickase Plasmid (h) - sc-400832-NIC from Santa Cruz Biotechnology
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HSPA2 Double Nickase Plasmid (h2) - sc-400832-NIC-2 from Santa Cruz Biotechnology
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HSPA2 CRISPR Activation Plasmid (h) - sc-400832-ACT from Santa Cruz Biotechnology
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HSPA2 CRISPR Activation Plasmid (h2) - sc-400832-ACT-2 from Santa Cruz Biotechnology
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HSPA2 Lentiviral Activation Particles (h) - sc-400832-LAC from Santa Cruz Biotechnology
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HSPA2 Lentiviral Activation Particles (h2) - sc-400832-LAC-2 from Santa Cruz Biotechnology
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HSPA2 siRNA (h) - sc-92302 from Santa Cruz Biotechnology
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HSPA2 shRNA Plasmid (h) - sc-92302-SH from Santa Cruz Biotechnology
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HSPA2 shRNA (h) Lentiviral Particles - sc-92302-V from Santa Cruz Biotechnology
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HSPA2 RNAi - H00003306-R01 from Novus Biologicals
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MISSION® esiRNA - EHU151051 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN10362 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND10362 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR04695 from Sigma-Aldrich
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HSPA2 siRNA (Human) - CRH2261 from Cohesion Biosciences
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HSPA2 - MBS8228953 from MyBioSource
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shRNA set against Human HSPA2 (NM_021979.3) - SHH315577 from Creative biogene
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shRNA set against Human HSPA2(NM_021979.3) - SHH134075 from Creative biogene
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Human HSPA2 siRNA - orb262763 from Biorbyt
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HSPA2 shRNA Plasmid (Human) - CHH2261 from Cohesion Biosciences
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HSPA2 miRNA 3'UTR clone - MiUTR1H-04734 from Creative biogene
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