MTHFD1L

Gene Symbol MTHFD1L
Entrez Gene 25902
Alt Symbol FTHFSDC1, MTC1THFS, dJ292B18.2
Species Human
Gene Type protein-coding
Description methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like
Other Description 10-formyl-THF synthetase|formyltetrahydrofolate synthetase domain containing 1|monofunctional C1-tetrahydrofolate synthase, mitochondrial
Swissprots Q2TBF3 Q8WVW0 Q9H789 Q9UFU8 Q96HG8 Q6UB35
Accessions CAM36319 CAM36320 CBF65969 CBF74049 CBU90841 CBU96477 EAW47760 EAW47761 EAW47762 EAW47763 Q6UB35 AA478842 AB127387 BAD93193 AK024798 BAB15009 AK127089 AK310342 AK315378 BAG37771 AL117452 CAB55934 AV704883 AW593866 AY374130 AAQ82696 AY374131 AAQ82697 BC008629 AAH08629 BC017477 AAH17477 BC110319 AAI10320 BC136685 AAI36686 BC144368 AAI44369 BC144369 BE735249 BQ062382 DA195967 DB727926 XM_005266907 XP_005266964 XM_005266910 XP_005266967 XM_005266911 XP_005266968 XM_011535729 XP_011534031 XM_011535730 XP_011534032 XM_011535731 XP_011534033 XM_011535732 XP_011534034 XM_011535733 XP_011534035 XM_011535734 XP_011534036 XM_011535735 XP_011534037 XM_011535736 XP_011534038 XM_011535737 XP_011534039 XM_011535738 XP_011534040 NM_001242767 NP_001229696 NM_001242768 NP_001229697 NM_001242769 NP_001229698 NM_015440 NP_056255
Function May provide the missing metabolic reaction required to link the mitochondria and the cytoplasm in the mammalian model of one-carbon folate metabolism in embryonic an transformed cells complementing thus the enzymatic activities of MTHFD2. {ECO:0000250}.
Subcellular Location Mitochondrion {ECO:0000269|PubMed:12937168}.
Tissue Specificity Detected in most tissues, highest expression found in placenta, thymus and brain. Low expression is found in liver and skeletal muscle. Up-regulated in colon adenocarcinoma. {ECO:0000269|PubMed:12937168, ECO:0000269|PubMed:15013446}.
Top Pathways One carbon pool by folate

MTHFD1L (6C7) - sc-100783 from Santa Cruz Biotechnology

Prices $295.00
Sizes 50 µg/0.5 ml
Host Mouse
Clonality Monoclonal
MTHFD1L (6C7): sc-100783. Western blot analysis of MTHFD1L expression in PC-12 whole cell lysate.

MTHFD1L (H-106) - sc-367843 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
MTHFD1L (H-106): sc-367843. Western blot analysis of MTHFD1L expression in PC-12 (A), HeLa (B), NIH/3T3 (C), C2C12 (D) and Hep G2 (E) whole cell lysates and rat cerebellum tissue extract (F).

Anti-MTHFD1L antibody - ab153840 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-MTHFD1L antibody (ab153840) at 1/1000 dilution + Hela whole cell lysate at 30 µg

Anti-FTHFSDC1 / MTHFD1L Antibody (aa801-900, Azide-free) - LS-C330536 from LifeSpan Bioscience

Host Mouse
Clonality Monoclonal

Anti-FTHFSDC1 / MTHFD1L Antibody (aa578-591) IHC-plus™ - LS-B9540 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Goat
Clonality Polyclonal
Anti-FTHFSDC1 / MTHFD1L antibody IHC staining of human tonsil. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B9540 concentration 5 ug/ml.

MTHFD1L Antibody - NBP2-37864 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: MTHFD1L Antibody [NBP2-37864] - Lane 1: Marker [kDa] 230, 130, 95, 72, 56, 36, 28, 17, 11. Lane 2: Human cell line RT-4. Lane 3: Human cell line U-251MG

MTHFD1L Antibody - NBP2-37863 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: MTHFD1L Antibody [NBP2-37863] - Lane 1: Marker [kDa] 230, 130, 95, 72, 56, 36, 28, 17, 11. Lane 2: Human cell line RT-4. Lane 3: Human cell line U-251MG

MTHFD1L Antibody - NBP2-15026 from Novus Biologicals

Prices $349.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: MTHFD1L Antibody [NBP2-15026] - Sample (30 ug of whole cell lysate) A: HeLa 10% SDS PAGE; antibody diluted at 1:1000.

MTHFD1L Antibody (1E8) - H00025902-M01 from Novus Biologicals

Prices $359.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 1E8
Western Blot: MTHFD1L Antibody (1E8) [H00025902-M01] - MTHFD1L monoclonal antibody (M01), clone 1E8 Analysis of MTHFD1L expression in PC-12.

MTHFD1L Antibody - NBP1-78279 from Novus Biologicals

Prices $299.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
Western Blot: MTHFD1L Antibody [NBP1-78279] (0.1ug/ml) staining of Human Cer(35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

MTHFD1L Antibody - H00025902-A01 from Novus Biologicals

Prices $269.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal

Monoclonal Anti-MTHFD1L antibody produced in mouse - WH0025902M1 from Sigma-Aldrich

Prices $347.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 1E8
<B>Immunoblotting</B><BR/>Monoclonal Anti-MTHFD1L, <B>Cat. No. WH0025902M1</B> used at the antibody concentration: 1 ~ 5 μg/mL. Specific band of ~105.7 kDa using PC-12 lysate.

Anti-MTHFD1L antibody produced in goat - SAB2501849 from Sigma-Aldrich

Prices $376.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-MTHFD1L: <B>Cat. No. SAB2501849</B>: (0.1 μg/mL) staining of Human Cerebellum lysate (35 μg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Anti-MTHFD1L antibody produced in rabbit - SAB2700590 from Sigma-Aldrich

Prices $326.50
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-MTHFD1L: <B>Cat. No. SAB2700590</B>: Western Blot analysis of MTHFD1L in extracts from <B>Lanes</B><BR/>A. HeLa using <B>Cat. No. SAB2700590</B> at a 1:1000 dilution.

MTHFD1L-Antibody-monoclonal-M01 - AT2927a from Abgent, a WuXi AppTec company

Prices $315.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 1E9
Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (36.63 KDa) .

MTHFD1L-aa535-538-Antibody-internal-region - AF3538a from Abgent, a WuXi AppTec company

Prices $335.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
AF3538a (0.1 µg/ml) staining of Human Cerebellum lysate (35 µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

MTHFD1L antibody [C1C2], Internal - GTX119126 from GeneTex

Prices $119.00
Sizes 25 μl
Host Rabbit
Clonality Polyclonal
Anti-MTHFD1L antibody [C1C2], Internal used in Western blot. GTX119126

Goat anti-MTHFD1L (aa535-538) middle region Antibody (OAEB02790) - OAEB02790 from Aviva Systems Biology

Prices $289.00
Sizes 100 µg
Host Goat
Clonality Polyclonal

MTHFD1L antibody - 70R-18661 from Fitzgerald

Host Rabbit
Clonality Polyclonal

MTHFD1L Polyclonal Antibody - A4592 from ABclonal

Prices $200.00, $480.00
Sizes 50 µg, 200 µg
Host Rabbit
Clonality Polyclonal

MTHFD1L antibody - orb22509 from Biorbyt

Prices $408.00
Sizes 100 μg
Host Goat
Clonality Polyclonal
Western blot analysis of Human Cerebellum lysate (35

MTHFD1L antibody - orb185344 from Biorbyt

Prices $255.00, $340.00
Sizes 100 μg, 200 μg
Host Rabbit
Clonality Polyclonal

MTHFD1L Antibody - abx003452 from Abbexa

Host Rabbit
Clonality Polyclonal

MTHFD1L antibody - 16113-1-AP from Acris Antibodies

Prices $270.00
Sizes 150 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemical of paraffin-embedded human colon cancer using 16113-1-AP(MTHFD1L antibody) at dilution of 1:100 (under 40x lens)
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