Gene Symbol | MFSD8 |
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Entrez Gene | 256471 |
Alt Symbol | CCMD, CLN7 |
Species | Human |
Gene Type | protein-coding |
Description | major facilitator superfamily domain containing 8 |
Other Description | ceroid-lipofuscinosis, neuronal 7, late infantile|major facilitator superfamily domain-containing protein 8 |
Swissprots | Q8NHS3 Q8N2P3 B7Z205 B2RDM1 |
Accessions | EAX05193 EAX05194 EAX05195 Q8NHS3 AA242881 AK074564 BAC11062 AK294184 BAH11691 AK294439 BAH11766 AK294527 BAH11798 AK294957 BAH11934 AK315596 BAG37968 BC029503 AAH29503 BI553701 BQ015234 CB956202 CN310788 CX873070 DA481070 JF432263 ADZ15480 XM_005262893 XP_005262950 XM_005262896 XP_005262953 XM_005262897 XP_005262954 XM_005262898 XP_005262955 XM_005262900 XP_005262957 XM_011531830 XP_011530132 XM_011531831 XP_011530133 XM_011531832 XP_011530134 XR_938717 NM_152778 NP_689991 |
Function | May be a carrier that transport small solutes by using chemiosmotic ion gradients. {ECO:0000305}. |
Subcellular Location | Lysosome membrane {ECO:0000269|PubMed:17564970, ECO:0000269|PubMed:17897319, ECO:0000269|PubMed:20406422}; Multi-pass membrane protein {ECO:0000269|PubMed:17564970, ECO:0000269|PubMed:17897319, ECO:0000269|PubMed:20406422}. Note=Sorting to lysosomes involves tyrosine- and/or dileucine-based motifs. |
Tissue Specificity | Expressed at very low levels in all tissues tested. {ECO:0000269|PubMed:17564970}. |
Top Pathways | Lysosome |
MFSD8 (S-14) - sc-165012 from Santa Cruz Biotechnology
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Anti-MFSD8 antibody - ab108231 from Abcam
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Anti-MFSD8 Antibody (aa351-400) - LS-C117154 from LifeSpan Bioscience
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MFSD8 Antibody - NBP1-92114 from Novus Biologicals
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MFSD8 Antibody - NBP1-79595 from Novus Biologicals
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Anti-MFSD8 antibody produced in rabbit - HPA044802 from Sigma-Aldrich
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Anti-MFSD8 antibody produced in rabbit - SAB2107128 from Sigma-Aldrich
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MFSD8 antibody - middle region (ARP55547_P050) - ARP55547_P050 from Aviva Systems Biology
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MFSD8 antibody - 70R-9335 from Fitzgerald
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MFSD8 antibody - 24298-1-AP from Acris Antibodies
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MFSD8 antibody - H00256471-B01P from Acris Antibodies
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MFSD8 antibody - 24298-1-AP from Proteintech Group
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MFSD8 Antibody - GWB-MT897F from Genway Biotech
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MFSD8-antibody-middle-region-AI13813 - AI13813 from Abgent, a WuXi AppTec company
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MFSD8, Polyclonal Antibody - MBS5303409 from MyBioSource
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MFSD8 antibody - TA329797 from Acris Antibodies
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MFSD8 Antibody,Biotin conjugated - CSB-PA844087LD01HU from Cusabio
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MFSD8 Antibody,FITC conjugated - CSB-PA844087LC01HU from Cusabio
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MFSD8 Antibody,HRP conjugated - CSB-PA844087LB01HU from Cusabio
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MFSD8 Antibody - CSB-PA844087LA01HU from Cusabio
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MFSD8 antibody (Biotin) - orb35695 from Biorbyt
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anti-MFSD8 antibody - A005155 from Biobool
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Anti-MFSD8 (aa 351-400) polyclonal antibody - CABT-BL2386 from Creative Diagnostics
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Anti-MFSD8 polyclonal antibody - CABT-BL2387 from Creative Diagnostics
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Anti-MFSD8 Antibody A06398 - A06398 from Boster Bio
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