Gene Symbol |
SLC8A2
|
Entrez Gene |
6543
|
Alt Symbol |
NCX2
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
solute carrier family 8 (sodium/calcium exchanger), member 2
|
Other Description |
Na(+)/Ca(2+)-exchange protein 2|Na+/Ca2+-exchanging protein Nac2|sodium-calcium exchanger 2|sodium/calcium exchanger 2|solute carrier family 8 (sodium-calcium exchanger), member 2|solute carrier family 8 member 2
|
Swissprots |
Q9UPR5 B4DYQ9
|
Accessions |
EAW57484 EAW57485 EAW57486 Q9UPR5 AB029010 BAA83039 AK293457 BAG56952 AK293836 BAG57237 AK293860 BAG57255 AK302552 BAG63821 AL512764 CAC21681 BC167838 AAI67838 DC401065 XM_005259172 XP_005259229 NM_015063 NP_055878
|
Function |
Rapidly transports Ca(2+) during excitation-contraction coupling. Ca(2+) is extruded from the cell during relaxation so as to prevent overloading of intracellular stores (By similarity). {ECO:0000250}.
|
Subcellular Location |
Membrane; Multi-pass membrane protein.
|
Top Pathways |
Calcium signaling pathway, Protein digestion and absorption, cGMP-PKG signaling pathway
|