Gene Symbol | SLC8A2 |
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Entrez Gene | 6543 |
Alt Symbol | NCX2 |
Species | Human |
Gene Type | protein-coding |
Description | solute carrier family 8 (sodium/calcium exchanger), member 2 |
Other Description | Na(+)/Ca(2+)-exchange protein 2|Na+/Ca2+-exchanging protein Nac2|sodium-calcium exchanger 2|sodium/calcium exchanger 2|solute carrier family 8 (sodium-calcium exchanger), member 2|solute carrier family 8 member 2 |
Swissprots | Q9UPR5 B4DYQ9 |
Accessions | EAW57484 EAW57485 EAW57486 Q9UPR5 AB029010 BAA83039 AK293457 BAG56952 AK293836 BAG57237 AK293860 BAG57255 AK302552 BAG63821 AL512764 CAC21681 BC167838 AAI67838 DC401065 XM_005259172 XP_005259229 NM_015063 NP_055878 |
Function | Rapidly transports Ca(2+) during excitation-contraction coupling. Ca(2+) is extruded from the cell during relaxation so as to prevent overloading of intracellular stores (By similarity). {ECO:0000250}. |
Subcellular Location | Membrane; Multi-pass membrane protein. |
Top Pathways | Calcium signaling pathway, Protein digestion and absorption, cGMP-PKG signaling pathway |
NCX2 CRISPR/Cas9 KO Plasmid (h) - sc-403352 from Santa Cruz Biotechnology
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NCX2 HDR Plasmid (h) - sc-403352-HDR from Santa Cruz Biotechnology
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NCX2 Double Nickase Plasmid (h) - sc-403352-NIC from Santa Cruz Biotechnology
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NCX2 Double Nickase Plasmid (h2) - sc-403352-NIC-2 from Santa Cruz Biotechnology
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NCX2 CRISPR Activation Plasmid (h) - sc-403352-ACT from Santa Cruz Biotechnology
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NCX2 CRISPR Activation Plasmid (h2) - sc-403352-ACT-2 from Santa Cruz Biotechnology
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NCX2 Lentiviral Activation Particles (h) - sc-403352-LAC from Santa Cruz Biotechnology
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NCX2 Lentiviral Activation Particles (h2) - sc-403352-LAC-2 from Santa Cruz Biotechnology
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NCX2 siRNA (h) - sc-44908 from Santa Cruz Biotechnology
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NCX2 shRNA Plasmid (h) - sc-44908-SH from Santa Cruz Biotechnology
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NCX2 shRNA (h) Lentiviral Particles - sc-44908-V from Santa Cruz Biotechnology
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SLC8A2 RNAi - H00006543-R01 from Novus Biologicals
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CompoZr® Knockout ZFN Kit - CKOZFN19697 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND19697 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR09272 from Sigma-Aldrich
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SLC8A2 siRNA (Human) - CRH4436 from Cohesion Biosciences
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SLC8A2 - MBS8215415 from MyBioSource
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shRNA set against Human Slc8a2 (NM_015063.2) - SHH412232 from Creative biogene
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SLC8A2 shRNA Plasmid (Human) - CHH4436 from Cohesion Biosciences
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