KATNA1

Gene Symbol KATNA1
Entrez Gene 11104
Alt Symbol -
Species Human
Gene Type protein-coding
Description katanin p60 (ATPase containing) subunit A 1
Other Description katanin p60 (ATPase-containing) subunit A 1|katanin p60 ATPase-containing subunit A1|katanin p60 subunit A1|p60 katanin
Swissprots E1P5A3 Q86VN2 O75449 Q5TFA9 Q9NU52 Q5TFA8
Accessions EAW47793 EAW47794 EAW47795 O75449 AF056022 AAC25114 AK292090 BAF84779 BC050428 AAH50428 CA426364 DB031858 XM_005266804 XP_005266861 XM_005266805 XP_005266862 XM_011535397 XP_011533699 NM_001204076 NP_001191005 NM_007044 NP_008975
Function Catalytic subunit of a complex which severs microtubules in an ATP-dependent manner. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation. Microtubule release from the mitotic spindle poles may allow depolymerization of the microtubule end proximal to the spindle pole, leading to poleward microtubule flux and poleward motion of chromosome. Microtubule release within the cell body of neurons may be required for their transport into neuronal processes by microtubule-dependent motor proteins. This transport is required for axonal growth. {ECO:0000255|HAMAP-Rule:MF_03023}.
Subcellular Location Cytoplasm. Midbody. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000255|HAMAP- Rule:MF_03023}. Cytoplasm, cytoskeleton, spindle pole. Note=Predominantly cytoplasmic. Localized diffusely in the cytoplasm during the interphase. During metaphase is localized throughout the cell and more widely dispersed than the microtubules. In anaphase and telophase is localized at the midbody region. Also localized to the interphase centrosome and the mitotic spindle poles. Enhanced recruitment to the mitotic spindle poles requires microtubules and interaction with KATNB1.

Katanin p60 A1 (M-13) - sc-109299 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
Katanin p60 A1 (M-13): sc-109299. Western blot analysis of Katanin p60 A1 expression in 293T (A), HeLa (B) and SK-N-MC (C) whole cell lysates.

Katanin p60 A1 (S-19) - sc-109302 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Katanin p60 A1 (D-14) - sc-109298 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-KATNA1 antibody - ab67206 from Abcam

Prices $370.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
All lanes : Anti-KATNA1 antibody (ab67206)Lane 1 : KATNA1 transfected 293T cell lysateLane 2 : Non transfected 293T cell lysate

Anti-KATNA1 antibody - ab118194 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-KATNA1 antibody (ab118194) at 1/1000 dilutionLane 1 : Human fetal brain lysateLane 2 : Human fetal liver lysate

Anti-KATNA1 antibody [EPR5071] - ab111881 from Abcam

Prices $313.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR5071
All lanes : Anti-KATNA1 antibody [EPR5071] (ab111881) at 1/1000 dilutionLane 1 : HeLa cell lysateLane 2 : HepG2 cell lysateLysates/proteins at 10 µg per lane.SecondaryHRP labelled goat anti-rabbit at 1/2000 dilution

Anti-KATNA1 antibody - N-terminal - ab138639 from Abcam

Prices $370.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-KATNA1 antibody - N-terminal (ab138639) at 1/100 dilution + 293 cell lysate at 35 µg

Anti-KATNA1 Antibody (aa59-85, AP) - LS-C222950 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-KATNA1 Antibody (aa59-85, APC) - LS-C222951 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-KATNA1 Antibody (aa59-85, Biotin) - LS-C222952 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-KATNA1 Antibody (aa59-85, FITC) - LS-C222953 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-KATNA1 Antibody - LS-C155604 from LifeSpan Bioscience

Prices $335.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Sample (30 ug of whole cell lysate) A: HepG2 10% SDS PAGE KATNA1 antibody diluted at 1:1000

Anti-KATNA1 Antibody (aa59-85, PE) - LS-C222955 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-KATNA1 Antibody (aa59-85, Azide-free, HRP) - LS-C222954 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-KATNA1 Antibody - LS-C308582 from LifeSpan Bioscience

Prices $455.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal

Anti-KATNA1 Antibody (aa349-398) - LS-C135274 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
KATNA1 antibody LS-C135274 Western blot of Mouse Spleen lysate. Antibody concentration 1 ug/ml.

Anti-KATNA1 Antibody - LS-C311304 from LifeSpan Bioscience

Prices $475.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-KATNA1 Antibody (aa58-85) - LS-C322355 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-KATNA1 Antibody (aa59-85) - LS-C159964 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
KATNA1 Antibody western blot of 293 cell line lysates (35 ug/lane). The KATNA1 antibody detected the KATNA1 protein (arrow).

Anti-KATNA1 Antibody (aa103-283) - LS-C178733 from LifeSpan Bioscience

Prices $255.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-KATNA1 Antibody (C-Terminus, clone EPR5071) - LS-C137859 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR5071
Western blot analysis on (A) HeLa and (B) HepG2 cell lysates using anti-KATNA1 antibody.

Anti-KATNA1 Antibody (Internal) - LS-C345576 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Western blot of KATNA1 Antibody with human MCF7 Whole Cell lysate.

Katanin p60 Antibody (717705) - MAB7100 from Novus Biologicals

Prices $99.00, $249.00
Sizes 25 µg, 100 µg
Host Mouse
Clonality Monoclonal
Clone 717705
Katanin p60 was detected in immersion fixed paraffin-embedded sections of human brain (globus pallidus) using Mouse Anti-Human Katanin p60 Monoclonal Antibody (Catalog # MAB7100) at 15 µg/mL overnight at 4 °C. Before incubation with the primary antibody, tissue was subjected to heat-induced epitope retrieval using Antigen Retrieval Reagent-Basic (Catalog # CTS013). Tissue was stained using the Anti-Mouse HRP-DAB Cell & Tissue Staining Kit (brown; Catalog # CTS002) and counterstained with hematoxylin (blue). Specific staining was localized to synaptic puncta. View our protocol for Chromogenic IHC Staining of Paraffin-embedded Tissue Sections.

Katanin p60 Antibody - AF7100 from Novus Biologicals

Prices $99.00, $359.00
Sizes 25 µg, 100 µg
Host Sheep
Clonality Polyclonal
Katanin p60 was detected in immersion fixed paraffin-embedded sections of human brain (globus pallidus) using Sheep Anti-Human Katanin p60 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF7100) at 3 µg/mL overnight at 4 °C. Before incubation with the primary antibody, tissue was subjected to heat-induced epitope retrieval using Antigen Retrieval Reagent-Basic (Catalog # CTS013). Tissue was stained using the Anti-Sheep HRP-DAB Cell & Tissue Staining Kit (brown; Catalog # CTS019) and counter­stained with hematoxylin (blue). Specific staining was localized to neuronal cell bodies and processes. View our protocol for Chromogenic IHC Staining of Paraffin-embedded Tissue Sections.

Katanin p60 Antibody - NBP1-89491 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunocytochemistry/Immunofluorescence: Katanin p60 Antibody [NBP1-89491] - Staining of human cell line U-251 MG shows positivity in nucleus but not nucleoli & centrosome.
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