| Gene Symbol |
AKAP17A
|
| Entrez Gene |
8227
|
| Alt Symbol |
721P, AKAP-17A, CCDC133, CXYorf3, DXYS155E, PRKA17A, SFRS17A, XE7, XE7Y
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
A kinase (PRKA) anchor protein 17A
|
| Other Description |
A-kinase anchor protein 17A|B-lymphocyte surface antigen|protein kinase A-anchoring protein 17A|pseudoautosomal gene XE7|splicing factor, arginine/serine-rich 17A
|
| Swissprots |
Q02040 Q5JQ74 Q8N6U9 Q2TB98 Q5JQ76 Q02832
|
| Accessions |
EAW98687 Q02040 AK308367 BC015800 BC016935 AAH16935 BC028151 AAH28151 BC110496 AAI10497 BC110497 AAI10498 BM046630 BM713425 L03426 AAA61303 M99578 AAA36187 NM_005088 NP_005079 NR_027383
|
| Function |
Splice factor regulating alternative splice site selection for certain mRNA precursors. Mediates regulation of pre- mRNA splicing in a PKA-dependent manner. {ECO:0000269|PubMed:16982639, ECO:0000269|PubMed:19840947}.
|
| Subcellular Location |
Nucleus speckle {ECO:0000269|PubMed:16982639, ECO:0000269|PubMed:19840947}.
|
| Tissue Specificity |
Widely expressed. Found in heart, brain, lung, liver, skeletal muscle, kidney and pancreas. Expressed in activated B-cells and placenta. Expressed in all cell lines tested including Jurkat-TAg, U-937 and HEK293 cells. {ECO:0000269|PubMed:19840947}.
|