Gene Symbol | AKAP17A |
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Entrez Gene | 8227 |
Alt Symbol | 721P, AKAP-17A, CCDC133, CXYorf3, DXYS155E, PRKA17A, SFRS17A, XE7, XE7Y |
Species | Human |
Gene Type | protein-coding |
Description | A kinase (PRKA) anchor protein 17A |
Other Description | A-kinase anchor protein 17A|B-lymphocyte surface antigen|protein kinase A-anchoring protein 17A|pseudoautosomal gene XE7|splicing factor, arginine/serine-rich 17A |
Swissprots | Q02040 Q5JQ74 Q8N6U9 Q2TB98 Q5JQ76 Q02832 |
Accessions | EAW98687 Q02040 AK308367 BC015800 BC016935 AAH16935 BC028151 AAH28151 BC110496 AAI10497 BC110497 AAI10498 BM046630 BM713425 L03426 AAA61303 M99578 AAA36187 NM_005088 NP_005079 NR_027383 |
Function | Splice factor regulating alternative splice site selection for certain mRNA precursors. Mediates regulation of pre- mRNA splicing in a PKA-dependent manner. {ECO:0000269|PubMed:16982639, ECO:0000269|PubMed:19840947}. |
Subcellular Location | Nucleus speckle {ECO:0000269|PubMed:16982639, ECO:0000269|PubMed:19840947}. |
Tissue Specificity | Widely expressed. Found in heart, brain, lung, liver, skeletal muscle, kidney and pancreas. Expressed in activated B-cells and placenta. Expressed in all cell lines tested including Jurkat-TAg, U-937 and HEK293 cells. {ECO:0000269|PubMed:19840947}. |
Human SFRS17A full length protein - ab159972 from Abcam
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Human SFRS17A protein fragment - ab159973 from Abcam
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AKAP17A / 721P Antibody Blocking Peptide - LS-E781 from LifeSpan Bioscience
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AKAP17A / 721P Antibody Blocking Peptide - LS-E12110 from LifeSpan Bioscience
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Recombinant Human XE7 Protein - H00008227-P01 from Novus Biologicals
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Recombinant Human XE7 Protein - H00008227-Q01 from Novus Biologicals
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SFRS17A-Antibody-Center-Blocking-peptide - BP11133c from Abgent, a WuXi AppTec company
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AKAP17A Blocking Peptide - abx063459 from Abbexa
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SFRS17A - H00008227-Q01-10 from Acris Antibodies
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SFRS17A - H00008227-Q01-25 from Acris Antibodies
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SFRS17A fusion protein - Ag4252 from Proteintech Group
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AKAP17A Blocking Peptide - CBP2265 from Cohesion Biosciences
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SFRS17A Protein - abx164952 from Abbexa
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XE7 Recombinant Protein Antigen - NBP1-92599PEP from Novus Biologicals
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AKAP17A Peptide, Human - M34GP00436H from Creative Peptides
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XE7 Recombinant Protein Antigen - NBP2-56088PEP from Novus Biologicals
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AKAP17A peptide - orb218128 from Biorbyt
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