NPHS1

Gene Symbol NPHS1
Entrez Gene 4868
Alt Symbol CNF, NPHN, nephrin
Species Human
Gene Type protein-coding
Description nephrosis 1, congenital, Finnish type (nephrin)
Other Description nephrin|renal glomerulus-specific cell adhesion receptor
Swissprots C3RX61 O60500 A6NDH2
Accessions AAB80768 O60500 AF035835 AAC39687 AF126957 AAF36451 AF190637 AAG17141 AK310731 BC156195 AAI56196 BC156935 AAI56936 BX103667 EU642886 ACH99862 EU642887 NM_004646 NP_004637
Function Seems to play a role in the development or function of the kidney glomerular filtration barrier. Regulates glomerular vascular permeability. May anchor the podocyte slit diaphragm to the actin cytoskeleton. Plays a role in skeletal muscle formation through regulation of myoblast fusion (By similarity). {ECO:0000250}.
Subcellular Location Cell membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}. Note=Predominantly located at podocyte slit diaphragm between podocyte foot processes. Also associated with podocyte apical plasma membrane. {ECO:0000269|PubMed:10393930, ECO:0000269|PubMed:10550324}.
Tissue Specificity Specifically expressed in podocytes of kidney glomeruli.

nephrin CRISPR/Cas9 KO Plasmid (h) - sc-400368 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

nephrin HDR Plasmid (h) - sc-400368-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

nephrin Double Nickase Plasmid (h) - sc-400368-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

nephrin Double Nickase Plasmid (h2) - sc-400368-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

nephrin CRISPR Activation Plasmid (h) - sc-400368-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

nephrin CRISPR Activation Plasmid (h2) - sc-400368-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

nephrin Lentiviral Activation Particles (h) - sc-400368-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

nephrin Lentiviral Activation Particles (h2) - sc-400368-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

nephrin siRNA (h) - sc-36030 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

nephrin shRNA Plasmid (h) - sc-36030-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

nephrin shRNA (h) Lentiviral Particles - sc-36030-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU094491 from Sigma-Aldrich

Category siRNA

MISSION® esiRNA - EHU096091 from Sigma-Aldrich

Category siRNA
Prices $250.00
Sizes 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN15454 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND15454 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR05584 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr05584

NPHS1 siRNA (Human) - CRH3237 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human NPHS1 (NM_004646.3) - SHH354248 from Creative biogene

Category siRNA
Species Reactivities Human

nephrin CRISPR/Cas9 KO Plasmid (h2) - sc-400368-KO-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

nephrin HDR Plasmid (h2) - sc-400368-HDR-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Human NPHS1 siRNA - orb263739 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

NPHS1 shRNA Plasmid (Human) - CHH3237 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

NPHS1 miRNA 3'UTR clone - MiUTR3H-05263 from Creative biogene

Species Reactivities Human
Search more