ARFGAP1

Gene Symbol	ARFGAP1
Entrez Gene	55738
Alt Symbol	ARF1GAP, HRIHFB2281
Species	Human
Gene Type	protein-coding
Description	ADP-ribosylation factor GTPase activating protein 1
Other Description	ADP-ribosylation factor GTPase-activating protein 1|ARF1-directed GTPase-activating protein
Swissprots	Q9UIL0 E7EV62 B7Z3U0 B7Z8H8 B7ZBI3 E1P5I9 Q9NSU3 Q6PK71 Q96KC4 Q8N6T3 Q96T02 Q9NVF6
Accessions	EAW75290 EAW75291 EAW75292 EAW75293 EAW75294 EAW75295 EAW75296 Q8N6T3 AA565406 AB015340 BAA88117 AK001629 BAA91796 AK027268 BAB55009 AK027441 BAB55113 AK095048 AK123367 AK123873 AK223427 BAD97147 AK296351 BAH12326 AK303454 BAH13964 AK308161 AL137744 CAB70901 AY927573 BC000786 AAH00786 BC006085 AAH06085 BC011876 AAH11876 BC028233 AAH28233 BC127893 BQ717837 DC300118 DC404137 HQ447319 ADQ31806 XM_006723823 XP_006723886 XM_011528901 XP_011527203 XM_011528902 XP_011527204 XR_936567 XR_936568 XR_936569 XR_936570 XR_936571 XR_936572 XR_936574 XR_936575 XR_936576 NM_001281482 NP_001268411 NM_001281483 NP_001268412 NM_001281484 NP_001268413 NM_018209 NP_060679 NM_175609 NP_783202 NR_104022 NR_104023
Function	GTPase-activating protein (GAP) for the ADP ribosylation factor 1 (ARF1). Involved in membrane trafficking and /or vesicle transport. Promotes hydrolysis of the ARF1-bound GTP and thus, is required for the dissociation of coat proteins from Golgi-derived membranes and vesicles, a prerequisite for vesicle's fusion with target compartment. Probably regulates ARF1-mediated transport via its interaction with the KDELR proteins and TMED2. Overexpression induces the redistribution of the entire Golgi complex to the endoplasmic reticulum, as when ARF1 is deactivated. Its activity is stimulated by phosphoinosides and inhibited by phosphatidylcholine (By similarity). {ECO:0000250}.
Subcellular Location	Cytoplasm {ECO:0000250}. Golgi apparatus {ECO:0000250}. Note=Associates with the Golgi complex. {ECO:0000250}.
Top Pathways	Endocytosis

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human ARFGAP1 full length protein - ab163196 from Abcam Category Protein Prices $402.00 Sizes 10 µg Source Wheat germ Species Human

Human ARFGAP1 full length protein - ab163197 from Abcam Category Protein Prices $402.00 Sizes 10 µg Source Wheat germ Species Human

ARFGAP1 Antibody Blocking Peptide - LS-E20843 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

ARFGAP1 Antibody Blocking Peptide - LS-E20844 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

ARFGAP1 Antibody Blocking Peptide - LS-E6934 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human ARFGAP1 Protein - H00055738-P02 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

Recombinant Human ARFGAP1 Protein - H00055738-P01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

ARFGAP1 Peptide - P1032 from Novus Biologicals Category Peptide Species Human

ARFGAP1-Antibody-Center-Blocking-Peptide - BP14738c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

ARFGAP1-Antibody-C-term-Blocking-Peptide - BP2303b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

ARFGAP3 blocking peptide - GTX89988-PEP from GeneTex Category Peptide Prices $239.00 Sizes 100 μg Species Human, Mouse, Dog, Rat, Bovine

ARFGAP1 Blocking Peptide - 33R-3508 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

ARFGAP1 Blocking Peptide - 33R-9999 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

ARFGAP1 - H00055738-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

ARFGAP1 - H00055738-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

ARFGAP1 - H00055738-P02 from Acris Antibodies Category Protein Prices $370.00 Sizes 10 µg Species Human

ARFGAP1 - H00055738-P02-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

ARFGAP1 - H00055738-P02-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

ARFGAP1 fusion protein - ag4468 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

ARF GAP1 (M204) Peptide - BS3066P from Bioworld Technology Category Peptide Prices $158.00 Sizes 100 µl

Recombinant Human ADP-ribosylation factor GTPase-activating protein 1(ARFGAP1) - CSB-YP843284HU CSB-EP843284HU CSB-BP843284HU CSB-MP843284HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

ADP-ribosylation factor GTPase-activating protein 1 (ARFGAP1) - MBS1301288 from MyBioSource Category Protein Prices $1,895.00, $1,895.00, $2,360.00, $2,360.00 Sizes 1 mg (E Coli Derived), 100 µg (Baculovirus Derived), 1 mg (Yeast Derived), 100 µg (Mammalian Cell Derived) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

ARFGAP1 (transcript variant 2) - TP306987 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

ARFGAP1 (transcript variant 1) - TP315268 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

ARFGAP1 Recombinant Protein Antigen - NBP2-14305PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

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