| Gene Symbol |
TRAF3IP1
|
| Entrez Gene |
26146
|
| Alt Symbol |
IFT54, MIP-T3, MIPT3
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
TNF receptor-associated factor 3 interacting protein 1
|
| Other Description |
TRAF3-interacting protein 1|interleukin 13 receptor alpha 1-binding protein-1|interleukin-13 receptor alpha 1-binding protein 1|intraflagellar transport protein 54 homolog|microtubule interacting protein that associates with TRAF3|microtubule-interacting protein associated with TRAF3|microtubule-interacting protein that associates with TRAF3
|
| Swissprots |
Q7L8N9 Q9Y4Q1 Q8TDR0 Q6PCT1 Q9NRD6
|
| Accessions |
AAX88977 EAW71156 EAW71157 Q8TDR0 AF230877 AAF76984 AF242456 AAL90444 AI356967 AL080153 CAB45744 BC059174 AAH59174 BX482493 XM_006712414 XP_006712477 XM_011510944 XP_011509246 XM_011510945 XP_011509247 XM_011510946 XP_011509248 XM_011510947 XP_011509249 XM_011510948 XP_011509250 XM_011510949 XP_011509251 XM_011510950 XP_011509252 XR_922902 NM_001139490 NP_001132962 NM_015650 NP_056465
|
| Function |
Plays an inhibitory role on IL13 signaling by binding to IL13RA1. Involved in suppression of IL13-induced STAT6 phosphorylation, transcriptional activity and DNA-binding. Recruits TRAF3 and DISC1 to the microtubules. {ECO:0000269|PubMed:10791955, ECO:0000269|PubMed:12812986, ECO:0000269|PubMed:12935900}.
|
| Subcellular Location |
Cytoplasm, cytoskeleton {ECO:0000269|PubMed:12935900}. Cell projection, cilium {ECO:0000250}. Note=Microtubules.
|
| Tissue Specificity |
Ubiquitous. {ECO:0000269|PubMed:12935900}.
|