Gene Symbol | TRAF3IP1 |
---|---|
Entrez Gene | 26146 |
Alt Symbol | IFT54, MIP-T3, MIPT3 |
Species | Human |
Gene Type | protein-coding |
Description | TNF receptor-associated factor 3 interacting protein 1 |
Other Description | TRAF3-interacting protein 1|interleukin 13 receptor alpha 1-binding protein-1|interleukin-13 receptor alpha 1-binding protein 1|intraflagellar transport protein 54 homolog|microtubule interacting protein that associates with TRAF3|microtubule-interacting protein associated with TRAF3|microtubule-interacting protein that associates with TRAF3 |
Swissprots | Q7L8N9 Q9Y4Q1 Q8TDR0 Q6PCT1 Q9NRD6 |
Accessions | AAX88977 EAW71156 EAW71157 Q8TDR0 AF230877 AAF76984 AF242456 AAL90444 AI356967 AL080153 CAB45744 BC059174 AAH59174 BX482493 XM_006712414 XP_006712477 XM_011510944 XP_011509246 XM_011510945 XP_011509247 XM_011510946 XP_011509248 XM_011510947 XP_011509249 XM_011510948 XP_011509250 XM_011510949 XP_011509251 XM_011510950 XP_011509252 XR_922902 NM_001139490 NP_001132962 NM_015650 NP_056465 |
Function | Plays an inhibitory role on IL13 signaling by binding to IL13RA1. Involved in suppression of IL13-induced STAT6 phosphorylation, transcriptional activity and DNA-binding. Recruits TRAF3 and DISC1 to the microtubules. {ECO:0000269|PubMed:10791955, ECO:0000269|PubMed:12812986, ECO:0000269|PubMed:12935900}. |
Subcellular Location | Cytoplasm, cytoskeleton {ECO:0000269|PubMed:12935900}. Cell projection, cilium {ECO:0000250}. Note=Microtubules. |
Tissue Specificity | Ubiquitous. {ECO:0000269|PubMed:12935900}. |