| Gene Symbol |
BDH2
|
| Entrez Gene |
56898
|
| Alt Symbol |
DHRS6, EFA6R, PRO20933, SDR15C1, UCPA-OR, UNQ6308
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
3-hydroxybutyrate dehydrogenase, type 2
|
| Other Description |
3-hydroxybutyrate dehydrogenase type 2|R-beta-hydroxybutyrate dehydrogenase|dehydrogenase/reductase (SDR family) member 6|dehydrogenase/reductase SDR family member 6|oxidoreductase UCPA|short chain dehydrogenase/reductase family 15C member 1|short chain dehydrogenase/reductase family 15C, member 1
|
| Swissprots |
Q6IA46 Q503A0 Q9BUT1 Q6UWD3 Q9NRX8 B4DUF6 Q9H8S8 A8K295
|
| Accessions |
CAC43884 CBF99640 CBG07667 CBG14351 CBV13160 CBV21189 CBV27865 EAX06163 EAX06164 EAX06165 EAX06166 EAX06167 EAX06168 Q9BUT1 AF164790 AAF80754 AK023323 BAB14526 AK128463 BAG54681 AK290160 BAF82849 AK291335 BAF84024 AK300626 BAG62318 AW136198 AY358841 AAQ89200 BC001953 AAH01953 BC037277 AAH37277 BC095414 AAH95414 BI544872 CR457309 CAG33590 XM_005263140 XP_005263197 XM_006714274 XP_006714337 XM_011532127 XP_011530429 XM_011532128 XP_011530430 NM_020139 NP_064524
|
| Function |
Dehydrogenase that mediates the formation of 2,5- dihydroxybenzoic acid (2,5-DHBA), a siderophore that shares structural similarities with bacterial enterobactin and associates with LCN2, thereby playing a key role in iron homeostasis and transport. Also acts as a 3-hydroxybutyrate dehydrogenase (By similarity). {ECO:0000250}.
|
| Subcellular Location |
Cytoplasm {ECO:0000269|PubMed:16380372}.
|
| Top Pathways |
Synthesis and degradation of ketone bodies, Butanoate metabolism
|