Gene Symbol | BDH2 |
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Entrez Gene | 56898 |
Alt Symbol | DHRS6, EFA6R, PRO20933, SDR15C1, UCPA-OR, UNQ6308 |
Species | Human |
Gene Type | protein-coding |
Description | 3-hydroxybutyrate dehydrogenase, type 2 |
Other Description | 3-hydroxybutyrate dehydrogenase type 2|R-beta-hydroxybutyrate dehydrogenase|dehydrogenase/reductase (SDR family) member 6|dehydrogenase/reductase SDR family member 6|oxidoreductase UCPA|short chain dehydrogenase/reductase family 15C member 1|short chain dehydrogenase/reductase family 15C, member 1 |
Swissprots | Q6IA46 Q503A0 Q9BUT1 Q6UWD3 Q9NRX8 B4DUF6 Q9H8S8 A8K295 |
Accessions | CAC43884 CBF99640 CBG07667 CBG14351 CBV13160 CBV21189 CBV27865 EAX06163 EAX06164 EAX06165 EAX06166 EAX06167 EAX06168 Q9BUT1 AF164790 AAF80754 AK023323 BAB14526 AK128463 BAG54681 AK290160 BAF82849 AK291335 BAF84024 AK300626 BAG62318 AW136198 AY358841 AAQ89200 BC001953 AAH01953 BC037277 AAH37277 BC095414 AAH95414 BI544872 CR457309 CAG33590 XM_005263140 XP_005263197 XM_006714274 XP_006714337 XM_011532127 XP_011530429 XM_011532128 XP_011530430 NM_020139 NP_064524 |
Function | Dehydrogenase that mediates the formation of 2,5- dihydroxybenzoic acid (2,5-DHBA), a siderophore that shares structural similarities with bacterial enterobactin and associates with LCN2, thereby playing a key role in iron homeostasis and transport. Also acts as a 3-hydroxybutyrate dehydrogenase (By similarity). {ECO:0000250}. |
Subcellular Location | Cytoplasm {ECO:0000269|PubMed:16380372}. |
Top Pathways | Synthesis and degradation of ketone bodies, Butanoate metabolism |
Human BDH2 full length protein - ab103058 from Abcam
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Human BDH2 peptide - ab96411 from Abcam
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BDH2 Antibody Blocking Peptide - LS-E26586 from LifeSpan Bioscience
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BDH2 Antibody Blocking Peptide - LS-E26622 from LifeSpan Bioscience
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BDH2 Antibody Blocking Peptide - LS-E20938 from LifeSpan Bioscience
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BDH2 Recombinant Protein - H00056898-P01 from Novus Biologicals
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Recombinant Human BDH2 Protein - NBP1-50963 from Novus Biologicals
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DHRS6-Antibody-C-term-Blocking-peptide - BP12766b from Abgent, a WuXi AppTec company
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BDH2/DHRS6 (aa 60 to 71) blocking peptide - GTX88892-PEP from GeneTex
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BDH2/DHRS6 (aa 92 to 103) blocking peptide - GTX88829-PEP from GeneTex
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PSD3 blocking peptide - GTX89531-PEP from GeneTex
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PSD3 (aa 327-339) blocking peptide - GTX88893-PEP from GeneTex
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PSD3 (aa 395-409) blocking peptide - GTX88888-PEP from GeneTex
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Human BDH2 protein - orb167968 from Biorbyt
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Goat anti BDH2 antibody Immunizing peptide - orb50403 from Biorbyt
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BDH2 Blocking Peptide - 33R-6852 from Fitzgerald
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BDH2 protein (His tag) - 80R-1640 from Fitzgerald
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BDH2 Peptide - AC21-1422-P from Abcore
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BDH2 Peptide - AC21-1458-P from Abcore
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BDH2 (1-245, His-tag) - AR09822PU-L from Acris Antibodies
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BDH2 (1-245, His-tag) - AR09822PU-N from Acris Antibodies
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BDH2 - H00056898-P01-10 from Acris Antibodies
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BDH2 - H00056898-P01-25 from Acris Antibodies
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3-Hydroxybutyrate Dehydrogenase, Type 2, Human Recombinant - 228-12212-1 from RayBiotech
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Recombinant Human 3-Hydroxybutyrate Dehydrogenase, Type 2 - 228-12212-2 from RayBiotech
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