Gene Symbol |
GABRA4
|
Entrez Gene |
2557
|
Alt Symbol |
-
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
gamma-aminobutyric acid (GABA) A receptor, alpha 4
|
Other Description |
GABA(A) receptor, alpha 4|gamma-aminobutyric acid A receptor alpha 4|gamma-aminobutyric acid receptor subunit alpha-4
|
Swissprots |
P48169 Q8IYR7
|
Accessions |
AAA74743 EAW93029 P48169 AF238869 AK090780 BAG52228 BC035055 AAH35055 BC036474 BC037926 BC042117 BI599812 CD013892 CD013893 DQ891679 ABM82605 DQ894864 ABM85790 EU176605 ABW03406 KJ534840 AHW56480 KJ535037 AHW56676 U30461 AAB52519 XM_011513677 XP_011511979 NM_000809 NP_000800 NM_001204266 NP_001191195 NM_001204267 NP_001191196
|
Function |
GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel.
|
Subcellular Location |
Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein.
|
Top Pathways |
GABAergic synapse, Morphine addiction, Nicotine addiction, Retrograde endocannabinoid signaling, Neuroactive ligand-receptor interaction
|