Gene Symbol | GABRA4 |
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Entrez Gene | 2557 |
Alt Symbol | - |
Species | Human |
Gene Type | protein-coding |
Description | gamma-aminobutyric acid (GABA) A receptor, alpha 4 |
Other Description | GABA(A) receptor, alpha 4|gamma-aminobutyric acid A receptor alpha 4|gamma-aminobutyric acid receptor subunit alpha-4 |
Swissprots | P48169 Q8IYR7 |
Accessions | AAA74743 EAW93029 P48169 AF238869 AK090780 BAG52228 BC035055 AAH35055 BC036474 BC037926 BC042117 BI599812 CD013892 CD013893 DQ891679 ABM82605 DQ894864 ABM85790 EU176605 ABW03406 KJ534840 AHW56480 KJ535037 AHW56676 U30461 AAB52519 XM_011513677 XP_011511979 NM_000809 NP_000800 NM_001204266 NP_001191195 NM_001204267 NP_001191196 |
Function | GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel. |
Subcellular Location | Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein. |
Top Pathways | GABAergic synapse, Morphine addiction, Nicotine addiction, Retrograde endocannabinoid signaling, Neuroactive ligand-receptor interaction |
GABA A Rα4 CRISPR/Cas9 KO Plasmid (h) - sc-417979 from Santa Cruz Biotechnology
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GABA A Rα4 HDR Plasmid (h) - sc-417979-HDR from Santa Cruz Biotechnology
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GABA A Rα4 Double Nickase Plasmid (h) - sc-417979-NIC from Santa Cruz Biotechnology
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GABA A Rα4 Double Nickase Plasmid (h2) - sc-417979-NIC-2 from Santa Cruz Biotechnology
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GABA A Rα4 CRISPR Activation Plasmid (h) - sc-417979-ACT from Santa Cruz Biotechnology
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GABA A Rα4 CRISPR Activation Plasmid (h2) - sc-417979-ACT-2 from Santa Cruz Biotechnology
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GABA A Rα4 Lentiviral Activation Particles (h) - sc-417979-LAC from Santa Cruz Biotechnology
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GABA A Rα4 Lentiviral Activation Particles (h2) - sc-417979-LAC-2 from Santa Cruz Biotechnology
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GABA A Rα4 siRNA (h) - sc-35433 from Santa Cruz Biotechnology
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GABA A Rα4 shRNA Plasmid (h) - sc-35433-SH from Santa Cruz Biotechnology
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GABA A Rα4 shRNA (h) Lentiviral Particles - sc-35433-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU038071 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN1821 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND1821 from Sigma-Aldrich
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GABRA4 siRNA (Human) - CRH1695 from Cohesion Biosciences
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GABA-A R alpha 4 RNAi - H00002557-R01 from Novus Biologicals
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GABRA4 - MBS8209835 from MyBioSource
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shRNA set against Human GABRA4 (NM_000809.3) - SHH298473 from Creative biogene
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Human GABRA4 siRNA - orb262197 from Biorbyt
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GABRA4 shRNA Plasmid (Human) - CHH1695 from Cohesion Biosciences
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