Il6

Gene Symbol Il6
Entrez Gene 16193
Alt Symbol Il-6
Species Mouse
Gene Type protein-coding
Description interleukin 6
Other Description B-cell hybridoma growth factor|interleukin HP-1|interleukin-6
Swissprots P08505 Q8BN26 Q3UCQ0
Accessions AAA39302 AAA68814 CAA35824 EDL37257 EDL37258 P08505 AK089780 AK150440 BAE29562 AK152189 BAE31020 BC132458 AAI32459 BC138766 AAI38767 BC145409 DQ788722 ABG81953 J03783 AAA39301 X06203 CAA29560 X54542 CAA38411 NM_031168 NP_112445
Function Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. Plays an essential role in the final differentiation of B-cells into Ig- secreting cells Involved in lymphocyte and monocyte differentiation. Acts on B-cells, T-cells, hepatocytes, hematopoietic progenitor cells and cells of the CNS. Required for the generation of T(H)17 cells. Also acts as a myokine. It is discharged into the bloodstream after muscle contraction and acts to increase the breakdown of fats and to improve insulin resistance. It induces myeloma and plasmacytoma growth and induces nerve cells differentiation. {ECO:0000269|PubMed:16990136}.
Subcellular Location Secreted.
Top Pathways TNF signaling pathway, Legionellosis, Herpes simplex infection, PI3K-Akt signaling pathway, African trypanosomiasis

IL-6 CRISPR/Cas9 KO Plasmid (m) - sc-421114 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

IL-6 HDR Plasmid (m) - sc-421114-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

IL-6 Double Nickase Plasmid (m) - sc-421114-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

IL-6 Double Nickase Plasmid (m2) - sc-421114-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

IL-6 CRISPR Activation Plasmid (m) - sc-421114-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

IL-6 CRISPR Activation Plasmid (m2) - sc-421114-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

IL-6 Lentiviral Activation Particles (m) - sc-421114-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

IL-6 Lentiviral Activation Particles (m2) - sc-421114-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

IL-6 siRNA (m) - sc-39628 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Mouse

IL-6 shRNA Plasmid (m) - sc-39628-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Mouse

IL-6 shRNA (m) Lentiviral Particles - sc-39628-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Mouse

MISSION® esiRNA - EMU011231 from Sigma-Aldrich

Category siRNA
Prices $250.00
Sizes 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN33805 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND33805 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

IL6 siRNA (Mouse) - CRM2067 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Mouse

IL6 - MBS8225600 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Mouse

shRNA set against Mouse IL6 (NM_031168.1) - SHH319049 from Creative biogene

Category siRNA
Species Reactivities Mouse

shRNA set against Mouse Il6(NM_031168.1) - SHL175982 from Creative biogene

Category siRNA
Species Reactivities Mouse

Mouse IL6 siRNA - orb281543 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Mouse

IL6 shRNA Plasmid (Mouse) - CHM2067 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Mouse

IL6 miRNA 3'UTR clone - MiUTR1M-06016 from Creative biogene

Species Reactivities Mouse
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