| Gene Symbol |
SHQ1
|
| Entrez Gene |
55164
|
| Alt Symbol |
Shq1p
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
SHQ1, H/ACA ribonucleoprotein assembly factor
|
| Other Description |
SHQ1 homolog|protein SHQ1 homolog
|
| Swissprots |
Q9NVS8 Q9H7E5 B4DL05 Q6PI26 Q7Z748 Q6MZJ4
|
| Accessions |
EAW65521 EAW65522 EAW65523 Q6PI26 AK001401 BAA91669 AK092962 AK296789 BAG59367 BC017204 AAH17204 BC017274 AAH17274 BC025270 AAH25270 BC032671 AAH32671 BC039830 AAH39830 BC047879 AAH47879 BX641074 CAE46037 XM_011533894 XP_011532196 XM_011533895 XP_011532197 XM_011533896 XP_011532198 XM_011533897 XP_011532199 XM_011533898 XP_011532200 XM_011533899 XP_011532201 NM_018130 NP_060600
|
| Function |
Required for the quantitative accumulation of H/ACA ribonucleoproteins (RNPs), including telomerase, probably through the stabilization of DKC1, from the time of its synthesis until its association with NOP10, NHP2, and NAF1 at the nascent H/ACA RNA. {ECO:0000269|PubMed:19383767}.
|
| Subcellular Location |
Cytoplasm, cytosol {ECO:0000269|PubMed:19383767}. Nucleus, nucleoplasm {ECO:0000269|PubMed:19383767}. Note=May at least partially shuttle between cytosol and nucleoplasm. In the nucleoplasm, exhibits a granular pattern, but is excluded from nucleoli and Cajal bodies. Absent from most H/ACA-box RNA transcription sites.
|