LARS

Gene Symbol LARS
Entrez Gene 51520
Alt Symbol HSPC192, ILFS1, LARS1, LEURS, LEUS, LFIS, LRS, PIG44, RNTLS, hr025Cl
Species Human
Gene Type protein-coding
Description leucyl-tRNA synthetase
Other Description cytoplasmic leucyl-tRNA synthetase|cytosolic leucyl-tRNA synthetase|leucine tRNA ligase 1, cytoplasmic|leucine translase|leucine--tRNA ligase, cytoplasmic|leucine-tRNA ligase|leucyl-tRNA synthetase, cytoplasmic|proliferation-inducing gene 44
Swissprots Q9NSE1 Q9P2J5 A7E266 A2RRR4 Q2TU79 B4DJ10
Accessions EAW61848 EAW61849 EAW61850 Q9P2J5 AB037773 BAA92590 AF151026 AAF36112 AK000277 AK001457 BAA91702 AK001682 BAA91833 AK021413 BAB13817 AK023777 BAB14674 AK025441 AK095870 AK127009 BAG54421 AK225372 AK293750 BAG57172 AK295874 BAG58672 AK304134 BAG65028 AK315178 BAG37619 AL390155 CAB99091 AY513284 AAT08037 AY926480 AAX10025 BC068041 AAH68041 BC105581 AAI05582 BC110084 BC131798 AAI31799 BC150213 AAI50214 BC151214 AAI51215 BC152422 AAI52423 CK902545 D84223 BAA95667 DB086913 U56252 XM_011537655 XP_011535957 XM_011537656 XP_011535958 XM_011537657 XP_011535959 NM_020117 NP_064502
Function Catalyzes the specific attachment of an amino acid to its cognate tRNA in a two step reaction: the amino acid (AA) is first activated by ATP to form AA-AMP and then transferred to the acceptor end of the tRNA. Exhibits a post-transfer editing activity to hydrolyze mischarged tRNAs. {ECO:0000269|PubMed:19426743}.
Subcellular Location Cytoplasm {ECO:0000250}.
Top Pathways Aminoacyl-tRNA biosynthesis

LARS Antibody - 13868 from Cell Signaling Technology

Prices $246.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts from various cell lines using LARS Antibody.

LeuRS (E-25) - sc-130801 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Rabbit
Clonality Polyclonal
LeuRS (E-25): sc-130801. Immunoperoxidase staining of formalin-fixed, paraffin-embedded human prostate carcinoma tissue showing cytoplasmic localization.

Anti-Leucyl tRNA synthetase antibody - ab31534 from Abcam

Prices $382.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-Leucyl tRNA synthetase antibody (ab31534) at 1/4000 dilutionLane 1 : Y79 (Human retinoblastoma cell line) Whole Cell Lysate Lane 2 : Raji (Human Burkitt's lymphoma cell line) Whole Cell Lysate Lysates/proteins at 10 µg per lane.SecondaryGoat polyclonal to Rabbit IgG - H&L - Pre-Adsorbed (HRP) at 1/3000 dilution

Anti-Leucyl tRNA synthetase antibody - C-terminal - ab176020 from Abcam

Prices $376.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemical analysis of formalin fixed, paraffin embedded Human prostate carcinoma tissue labeling Leucyl tRNA synthetase with ab176020 at 1/10, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining.

Anti-Leucyl tRNA synthetase antibody - N-terminal - ab200119 from Abcam

Host Rabbit
Clonality Polyclonal
All lanes : Anti-Leucyl tRNA synthetase antibody - N-terminal (ab200119) at 1/1000 dilutionLane 1 : Mouse brain total cell extractLane 2 : Mouse thymus total cell extractLane 3 : HeLa total cell extractLane 4 : Jurkat total cell extract

Anti-LARS / Leucyl-TRNA Synthetase Antibody (aa1-50) - LS-C290955 from LifeSpan Bioscience

Prices $375.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Detection of Human and Mouse LARS by Western Blot. Samples: Whole cell lysate (50 ug) from HeLa, 293T, Jurkat, mouse TCMK-1, and mouse NIH3T3 cells. Antibodies: Affinity purified rabbit anti-LARS antibody used for WB at 0.4 ug/ml. Detection: Chemiluminescence with an exposure time of 30 seconds.

Anti-LARS / Leucyl-TRNA Synthetase Antibody (aa250-300) - LS-C290957 from LifeSpan Bioscience

Prices $375.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Detection of Human and Mouse LARS by Western Blot. Samples: Whole cell lysate (50 ug) from HeLa, 293T, Jurkat, mouse TCMK-1, and mouse NIH3T3 cells. Antibodies: Affinity purified rabbit anti-LARS antibody used for WB at 0.4 ug/ml. Detection: Chemiluminescence with an exposure time of 30 seconds.

Anti-LARS / Leucyl-TRNA Synthetase Antibody (aa176-205) - LS-C165689 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
LARS Antibody western blot of mouse Neuro-2a cell line lysates (35 ug/lane). The LARS antibody detected the LARS protein (arrow).

Anti-LARS / Leucyl-TRNA Synthetase Antibody (aa1118-1145) - LS-C100610 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Formalin-fixed and paraffin-embedded human prostate carcinoma tissue reacted with LARS antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.

LARS Antibody - NBP2-38478 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: LARS Antibody [NBP2-38478] - Lane 1: Marker [kDa] 250, 130, 95, 72, 55, 36, 28, 17, 10. Lane 2: Human cell line RT-4. Lane 3: Human cell line U-251MG

LARS Antibody - NBP1-90430 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunocytochemistry/Immunofluorescence: LARS Antibody [NBP1-90430] - Staining of human cell line U-2 OS shows positivity in nucleus and cytoplasm.

LARS Antibody - NBP2-32209 from Novus Biologicals

Prices $359.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

LARS Antibody - NBP2-32208 from Novus Biologicals

Prices $379.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western Blot: LARS Antibody [NBP2-32208] - Samples: Whole cell lysate (50 ug) from HeLa, 293T, Jurkat, mouse TCMK-1, and mouse NIH3T3 cells. Antibodies: Affinity purified rabbit anti-LARS antibody NBP2-32208 used for WB at 0.4 ug/ml. Detection: Chemiluminescence with an exposure time of 30 seconds.

LARS Antibody - NBP2-19333 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-LARS (C-terminal) antibody produced in rabbit - SAB2701568 from Sigma-Aldrich

Prices $326.50
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-LARS (C-terminal): <B>Cat. No. SAB2701568</B>: Western Blot analysis of LARS in extracts from <B>Lanes</B><BR/>A. NT2D1 <BR/>B. PC-3 using <B>Cat. No. SAB2701568</B> at a 1:1000 dilution.

Anti-LARS (C-term) antibody produced in rabbit - SAB1300853 from Sigma-Aldrich

Prices $291.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-LARS (C-term) Antibody: <B>Cat. No. SAB1300853</B>: LARS in human prostate carcinoma tissue with Anti-LARS (C-term) Antibody at 40 μg/mL.

Anti-LARS antibody produced in rabbit - HPA036424 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-LARS: <B>Cat. No. HPA036424</B>: Immunohistochemical staining of human liver shows strong cytoplasmic positivity in bile duct cells.

LARS-Antibody-N-term - AP11207a from Abgent, a WuXi AppTec company

Prices $99.00, $295.00
Sizes 80 µl, 400 µl
Host Rabbit
Clonality Polyclonal
LARS Antibody (N-term) (Cat. #AP11207a) flow cytometric analysis of Hela cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.

LARS-Antibody-C-term - AP7413b from Abgent, a WuXi AppTec company

Prices $99.00, $295.00
Sizes 80 µl, 400 µl
Host Rabbit
Clonality Polyclonal
Western blot analysis of anti-LARS Antibody (C-term) (Cat.#AP7413b) in 293 cell line lysates (35ug/lane). LARS(arrow) was detected using the purified Pab.

LARS Antibody - C-terminal region (OAAB04427) - OAAB04427 from Aviva Systems Biology

Prices $289.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal

LARS Antibody - N-terminal region (OAAB07450) - OAAB07450 from Aviva Systems Biology

Prices $289.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal

LARS antibody [C2C3], C-term - GTX122744 from GeneTex

Prices $119.00
Sizes 25 μl
Host Rabbit
Clonality Polyclonal
Anti-LARS antibody [C2C3], C-term used in Western blot. GTX122744

LARS antibody, C-term - GTX81468 from GeneTex

Prices $319.00
Sizes 400 μl
Host Rabbit
Clonality Polyclonal
Anti-LARS antibody, C-term used in IHC (Formalin-fixed paraffin-embedded sections). GTX81468

LARS antibody - 70R-18216 from Fitzgerald

Prices $375.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal

LARS antibody - 21146-1-AP from Acris Antibodies

Prices $270.00
Sizes 150 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemical of paraffin-embedded human colon using 21146-1-AP(LARS antibody) at dilution of 1:100 (under 10x lens)
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