| Gene Symbol |
FLVCR2
|
| Entrez Gene |
55640
|
| Alt Symbol |
C14orf58, CCT, EPV, FLVCRL14q, MFSD7C, PVHH
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
feline leukemia virus subgroup C cellular receptor family, member 2
|
| Other Description |
calcium-chelate transporter|feline leukemia virus subgroup C receptor-related protein 2
|
| Swissprots |
B7Z485 Q9UPI3 Q53ZT9 Q96JY3 Q9NX90
|
| Accessions |
AAD51374 EAW81235 Q9UPI3 AF456126 AAO15528 AK000378 BAA91126 AK027804 BAB55381 AK297002 BAH12471 AY260572 AAP86633 AY260577 AAP86638 BC019087 AAH19087 BC026295 CR739521 DA166212 JF432805 ADZ16022 NM_001195283 NP_001182212 NM_017791 NP_060261
|
| Function |
Acts as an importer of heme. Also acts as a transporter for a calcium-chelator complex, important for growth and calcium metabolism. {ECO:0000269|PubMed:20823265}.
|
| Subcellular Location |
Cell membrane; Multi-pass membrane protein.
|
| Tissue Specificity |
Expressed in non-hematopoietic tissues, with relative abundant expression in brain, placenta, lung, liver and kidney. Also expressed in hematopoietic tissues (fetal liver, spleen, lymph node, thymus, leukocytes and bone marrow). Found in acidophil cells of the pituitary that secrete growth hormone and prolactin.
|
