Gene Symbol | FLVCR2 |
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Entrez Gene | 55640 |
Alt Symbol | C14orf58, CCT, EPV, FLVCRL14q, MFSD7C, PVHH |
Species | Human |
Gene Type | protein-coding |
Description | feline leukemia virus subgroup C cellular receptor family, member 2 |
Other Description | calcium-chelate transporter|feline leukemia virus subgroup C receptor-related protein 2 |
Swissprots | B7Z485 Q9UPI3 Q53ZT9 Q96JY3 Q9NX90 |
Accessions | AAD51374 EAW81235 Q9UPI3 AF456126 AAO15528 AK000378 BAA91126 AK027804 BAB55381 AK297002 BAH12471 AY260572 AAP86633 AY260577 AAP86638 BC019087 AAH19087 BC026295 CR739521 DA166212 JF432805 ADZ16022 NM_001195283 NP_001182212 NM_017791 NP_060261 |
Function | Acts as an importer of heme. Also acts as a transporter for a calcium-chelator complex, important for growth and calcium metabolism. {ECO:0000269|PubMed:20823265}. |
Subcellular Location | Cell membrane; Multi-pass membrane protein. |
Tissue Specificity | Expressed in non-hematopoietic tissues, with relative abundant expression in brain, placenta, lung, liver and kidney. Also expressed in hematopoietic tissues (fetal liver, spleen, lymph node, thymus, leukocytes and bone marrow). Found in acidophil cells of the pituitary that secrete growth hormone and prolactin. |
FLVCR2 CRISPR/Cas9 KO Plasmid (h) - sc-410019 from Santa Cruz Biotechnology
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FLVCR2 HDR Plasmid (h) - sc-410019-HDR from Santa Cruz Biotechnology
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FLVCR2 Double Nickase Plasmid (h) - sc-410019-NIC from Santa Cruz Biotechnology
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FLVCR2 Double Nickase Plasmid (h2) - sc-410019-NIC-2 from Santa Cruz Biotechnology
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FLVCR2 CRISPR Activation Plasmid (h) - sc-410019-ACT from Santa Cruz Biotechnology
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FLVCR2 CRISPR Activation Plasmid (h2) - sc-410019-ACT-2 from Santa Cruz Biotechnology
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FLVCR2 Lentiviral Activation Particles (h) - sc-410019-LAC from Santa Cruz Biotechnology
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FLVCR2 Lentiviral Activation Particles (h2) - sc-410019-LAC-2 from Santa Cruz Biotechnology
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FLVCR2 siRNA (h) - sc-92360 from Santa Cruz Biotechnology
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FLVCR2 shRNA Plasmid (h) - sc-92360-SH from Santa Cruz Biotechnology
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FLVCR2 shRNA (h) Lentiviral Particles - sc-92360-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU016021 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN8832 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND8832 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR10292 from Sigma-Aldrich
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FLVCR2 siRNA (Human) - CRJ0797 from Cohesion Biosciences
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FLVCR2 - MBS8203841 from MyBioSource
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shRNA set against Human FLVCR2 (NM_017791.2) - SHH295809 from Creative biogene
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Human FLVCR2 siRNA - orb271298 from Biorbyt
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FLVCR2 shRNA Plasmid (Human) - CHJ0797 from Cohesion Biosciences
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FLVCR2 miRNA 3'UTR clone - MiUTR3H-11516 from Creative biogene
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