| Gene Symbol |
H2BFWT
|
| Entrez Gene |
158983
|
| Alt Symbol |
-
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
H2B histone family, member W, testis-specific
|
| Other Description |
histone H2B type W-T
|
| Swissprots |
B1AK72 Q7Z2G1 Q147W3
|
| Accessions |
AAP37489 CAI43100 EAX02765 EAX02766 Q7Z2G1 AY283370 AAP37490 BC038109 AAH38109 BC118604 AAI18605 BC121816 AAI21817 NM_001002916 NP_001002916
|
| Function |
Atypical histone H2B. Nucleosomes containing it are structurally and dynamically indistinguishable from those containing conventional H2B. However, unlike conventional H2B, does not recruit chromosome condensation factors and does not participate in the assembly of mitotic chromosomes. May be important for telomere function. {ECO:0000269|PubMed:16449661}.
|
| Subcellular Location |
Nucleus membrane {ECO:0000269|PubMed:15475252}. Chromosome {ECO:0000269|PubMed:15475252}.
|
| Tissue Specificity |
Testis-specific. Present in sperm cells (at protein level). {ECO:0000269|PubMed:15475252}.
|
| Top Pathways |
Systemic lupus erythematosus, Viral carcinogenesis, Alcoholism
|
