| Gene Symbol |
QTRTD1
|
| Entrez Gene |
79691
|
| Alt Symbol |
-
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
queuine tRNA-ribosyltransferase domain containing 1
|
| Other Description |
queuine tRNA-ribosyltransferase subunit QTRTD1
|
| Swissprots |
Q9H974 Q6IA59 A6NGE9 B7Z5R2 J3KR78 B7Z472
|
| Accessions |
EAW79613 EAW79614 Q9H974 AK023022 BAB14361 AK296938 BAH12458 AK299313 BAH12998 AL832215 AL833709 BC034559 AAH34559 BC039265 AAH39265 CR457296 CAG33577 DC400836 HQ447265 ADQ31752 XM_005247769 XP_005247826 XM_005247770 XP_005247827 XM_006713744 XP_006713807 XM_011513137 XP_011511439 XM_011513138 XP_011511440 XM_011513139 XP_011511441 NM_001256835 NP_001243764 NM_001256836 NP_001243765 NM_001256837 NP_001243766 NM_024638 NP_078914
|
| Function |
Interacts with QTRT1 to form an active queuine tRNA- ribosyltransferase. This enzyme exchanges queuine for the guanine at the wobble position of tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr), thereby forming the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis-dihydroxy-2-cyclopenten-1- yl)amino)methyl)-7-deazaguanosine). {ECO:0000255|HAMAP- Rule:MF_03043}.
|
| Subcellular Location |
Cytoplasm {ECO:0000255|HAMAP-Rule:MF_03043}. Mitochondrion {ECO:0000255|HAMAP-Rule:MF_03043}. Note=May associate with the mitochondrion outer membrane. {ECO:0000255|HAMAP-Rule:MF_03043}.
|
![Western Blot: QTRTD1 Overexpression Lysate (Adult Normal) [NBL1-15035] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for QTRTD1.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/10006_QTRTD1%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBL1-15035-img0002.jpg)