Gene Symbol | QTRTD1 |
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Entrez Gene | 79691 |
Alt Symbol | - |
Species | Human |
Gene Type | protein-coding |
Description | queuine tRNA-ribosyltransferase domain containing 1 |
Other Description | queuine tRNA-ribosyltransferase subunit QTRTD1 |
Swissprots | Q9H974 Q6IA59 A6NGE9 B7Z5R2 J3KR78 B7Z472 |
Accessions | EAW79613 EAW79614 Q9H974 AK023022 BAB14361 AK296938 BAH12458 AK299313 BAH12998 AL832215 AL833709 BC034559 AAH34559 BC039265 AAH39265 CR457296 CAG33577 DC400836 HQ447265 ADQ31752 XM_005247769 XP_005247826 XM_005247770 XP_005247827 XM_006713744 XP_006713807 XM_011513137 XP_011511439 XM_011513138 XP_011511440 XM_011513139 XP_011511441 NM_001256835 NP_001243764 NM_001256836 NP_001243765 NM_001256837 NP_001243766 NM_024638 NP_078914 |
Function | Interacts with QTRT1 to form an active queuine tRNA- ribosyltransferase. This enzyme exchanges queuine for the guanine at the wobble position of tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr), thereby forming the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis-dihydroxy-2-cyclopenten-1- yl)amino)methyl)-7-deazaguanosine). {ECO:0000255|HAMAP- Rule:MF_03043}. |
Subcellular Location | Cytoplasm {ECO:0000255|HAMAP-Rule:MF_03043}. Mitochondrion {ECO:0000255|HAMAP-Rule:MF_03043}. Note=May associate with the mitochondrion outer membrane. {ECO:0000255|HAMAP-Rule:MF_03043}. |
QTRTD1 CRISPR/Cas9 KO Plasmid (h) - sc-413212 from Santa Cruz Biotechnology
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QTRTD1 HDR Plasmid (h) - sc-413212-HDR from Santa Cruz Biotechnology
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QTRTD1 Double Nickase Plasmid (h) - sc-413212-NIC from Santa Cruz Biotechnology
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QTRTD1 Double Nickase Plasmid (h2) - sc-413212-NIC-2 from Santa Cruz Biotechnology
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QTRTD1 CRISPR Activation Plasmid (h) - sc-413212-ACT from Santa Cruz Biotechnology
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QTRTD1 CRISPR Activation Plasmid (h2) - sc-413212-ACT-2 from Santa Cruz Biotechnology
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QTRTD1 Lentiviral Activation Particles (h) - sc-413212-LAC from Santa Cruz Biotechnology
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QTRTD1 Lentiviral Activation Particles (h2) - sc-413212-LAC-2 from Santa Cruz Biotechnology
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QTRTD1 siRNA (h) - sc-78408 from Santa Cruz Biotechnology
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QTRTD1 shRNA Plasmid (h) - sc-78408-SH from Santa Cruz Biotechnology
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QTRTD1 shRNA (h) Lentiviral Particles - sc-78408-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU028271 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN17796 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND17796 from Sigma-Aldrich
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QTRTD1 siRNA (Human) - CRJ2489 from Cohesion Biosciences
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QTRTD1 - MBS8200721 from MyBioSource
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shRNA set against Human QTRTD1 (NM_024638.3) - SHH387732 from Creative biogene
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Human QTRTD1 siRNA - orb272990 from Biorbyt
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QTRTD1 shRNA Plasmid (Human) - CHJ2489 from Cohesion Biosciences
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QTRTD1 miRNA 3'UTR clone - MiUTR4H-TG07252 from Creative biogene
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