| Gene Symbol |
TAF1A
|
| Entrez Gene |
9015
|
| Alt Symbol |
MGC:17061, RAFI48, SL1, TAFI48
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
TATA box binding protein (TBP)-associated factor, RNA polymerase I, A, 48kDa
|
| Other Description |
RNA polymerase I-specific TBP-associated factor 48 kDa|SL1, 48kD subunit|TATA box binding protein (TBP)-associated factor, RNA polymerase I, A, 48kD|TATA box-binding protein-associated factor 1A|TATA box-binding protein-associated factor RNA polymerase I subunit A|TBP-associated factor 1A|transcription factor SL1|transcription initiation factor SL1/TIF-IB subunit A
|
| Swissprots |
Q15573 B2RDZ8 Q9NWA1 D3DTB7
|
| Accessions |
CAE89061 EAW93271 EAW93272 EAW93273 Q15573 AK001054 BAA91482 AK290970 BAF83659 AK299536 BAG61483 AK307882 AK315740 BAG38095 BC013808 AAH13808 CN479053 DQ891081 ABM82007 DQ894263 ABM85189 L39060 AAA62862 XM_005273343 XP_005273400 XM_006711612 XP_006711675 XM_006711613 XP_006711676 XM_011510112 XP_011508414 NM_001201536 NP_001188465 NM_005681 NP_005672 NM_139352 NP_647603
|
| Function |
Component of the transcription factor SL1/TIF-IB complex, which is involved in the assembly of the PIC (preinitiation complex) during RNA polymerase I-dependent transcription. The rate of PIC formation probably is primarily dependent on the rate of association of SL1/TIF-IB with the rDNA promoter. SL1/TIF-IB is involved in stabilization of nucleolar transcription factor 1/UBTF on rDNA. Formation of SL1/TIF-IB excludes the association of TBP with TFIID subunits. {ECO:0000269|PubMed:15970593, ECO:0000269|PubMed:7801123}.
|
| Subcellular Location |
Nucleus.
|