Gene Symbol | TAF1A |
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Entrez Gene | 9015 |
Alt Symbol | MGC:17061, RAFI48, SL1, TAFI48 |
Species | Human |
Gene Type | protein-coding |
Description | TATA box binding protein (TBP)-associated factor, RNA polymerase I, A, 48kDa |
Other Description | RNA polymerase I-specific TBP-associated factor 48 kDa|SL1, 48kD subunit|TATA box binding protein (TBP)-associated factor, RNA polymerase I, A, 48kD|TATA box-binding protein-associated factor 1A|TATA box-binding protein-associated factor RNA polymerase I subunit A|TBP-associated factor 1A|transcription factor SL1|transcription initiation factor SL1/TIF-IB subunit A |
Swissprots | Q15573 B2RDZ8 Q9NWA1 D3DTB7 |
Accessions | CAE89061 EAW93271 EAW93272 EAW93273 Q15573 AK001054 BAA91482 AK290970 BAF83659 AK299536 BAG61483 AK307882 AK315740 BAG38095 BC013808 AAH13808 CN479053 DQ891081 ABM82007 DQ894263 ABM85189 L39060 AAA62862 XM_005273343 XP_005273400 XM_006711612 XP_006711675 XM_006711613 XP_006711676 XM_011510112 XP_011508414 NM_001201536 NP_001188465 NM_005681 NP_005672 NM_139352 NP_647603 |
Function | Component of the transcription factor SL1/TIF-IB complex, which is involved in the assembly of the PIC (preinitiation complex) during RNA polymerase I-dependent transcription. The rate of PIC formation probably is primarily dependent on the rate of association of SL1/TIF-IB with the rDNA promoter. SL1/TIF-IB is involved in stabilization of nucleolar transcription factor 1/UBTF on rDNA. Formation of SL1/TIF-IB excludes the association of TBP with TFIID subunits. {ECO:0000269|PubMed:15970593, ECO:0000269|PubMed:7801123}. |
Subcellular Location | Nucleus. |
TAF I p48 CRISPR/Cas9 KO Plasmid (h) - sc-418118 from Santa Cruz Biotechnology
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TAF I p48 HDR Plasmid (h) - sc-418118-HDR from Santa Cruz Biotechnology
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TAF I p48 Double Nickase Plasmid (h) - sc-418118-NIC from Santa Cruz Biotechnology
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TAF I p48 Double Nickase Plasmid (h2) - sc-418118-NIC-2 from Santa Cruz Biotechnology
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TAF I p48 CRISPR Activation Plasmid (h) - sc-418118-ACT from Santa Cruz Biotechnology
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TAF I p48 CRISPR Activation Plasmid (h2) - sc-418118-ACT-2 from Santa Cruz Biotechnology
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TAF I p48 Lentiviral Activation Particles (h) - sc-418118-LAC from Santa Cruz Biotechnology
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TAF I p48 Lentiviral Activation Particles (h2) - sc-418118-LAC-2 from Santa Cruz Biotechnology
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TAF I p48 siRNA (h) - sc-38486 from Santa Cruz Biotechnology
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TAF I p48 shRNA Plasmid (h) - sc-38486-SH from Santa Cruz Biotechnology
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TAF I p48 shRNA (h) Lentiviral Particles - sc-38486-V from Santa Cruz Biotechnology
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TAF148 RNAi - H00009015-R02 from Novus Biologicals
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MISSION® esiRNA - EHU077881 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN20965 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND20965 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR03117 from Sigma-Aldrich
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TAF1A siRNA (Human) - CRH5944 from Cohesion Biosciences
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TAF148 RNAi - H00009015-R01 from Novus Biologicals
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TAF1A - MBS8210223 from MyBioSource
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Human TAF1A siRNA - orb266446 from Biorbyt
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TAF1A shRNA Plasmid (Human) - CHH5944 from Cohesion Biosciences
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TAF1A miRNA 3'UTR clone - MiUTR4H-TG08736 from Creative biogene
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