Gene Symbol |
CCNE1
|
Entrez Gene |
898
|
Alt Symbol |
CCNE
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
cyclin E1
|
Other Description |
G1/S-specific cyclin-E1|cyclin E variant ex5del|cyclin E variant ex7del|cyclin Es|cyclin Et
|
Swissprots |
Q14091 P24864 Q9UD21 A8K684 Q92501 Q8NFG1
|
Accessions |
AAM54043 AEF32520 CAA64687 CAA64688 P24864 AK291549 BAF84238 AU137789 BC035498 AAH35498 BE645164 DQ893383 ABM84309 DQ896703 ABM87702 KF672847 AHC02488 KF672848 AHC02489 M73812 M74093 XM_005259370 XP_005259427 XM_006723457 XP_006723520 XM_011527440 XP_011525742 NM_001238 NP_001229 NM_057182
|
Function |
Essential for the control of the cell cycle at the G1/S (start) transition. {ECO:0000269|PubMed:7739542}.
|
Subcellular Location |
Nucleus {ECO:0000269|PubMed:7739542}.
|
Tissue Specificity |
Highly expressed in testis and placenta. Low levels in bronchial epithelial cells. {ECO:0000269|PubMed:9840943}.
|
Top Pathways |
Oocyte meiosis, Cell cycle, Measles, Viral carcinogenesis, PI3K-Akt signaling pathway
|