Gene Symbol | CCNE1 |
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Entrez Gene | 898 |
Alt Symbol | CCNE |
Species | Human |
Gene Type | protein-coding |
Description | cyclin E1 |
Other Description | G1/S-specific cyclin-E1|cyclin E variant ex5del|cyclin E variant ex7del|cyclin Es|cyclin Et |
Swissprots | Q14091 P24864 Q9UD21 A8K684 Q92501 Q8NFG1 |
Accessions | AAM54043 AEF32520 CAA64687 CAA64688 P24864 AK291549 BAF84238 AU137789 BC035498 AAH35498 BE645164 DQ893383 ABM84309 DQ896703 ABM87702 KF672847 AHC02488 KF672848 AHC02489 M73812 M74093 XM_005259370 XP_005259427 XM_006723457 XP_006723520 XM_011527440 XP_011525742 NM_001238 NP_001229 NM_057182 |
Function | Essential for the control of the cell cycle at the G1/S (start) transition. {ECO:0000269|PubMed:7739542}. |
Subcellular Location | Nucleus {ECO:0000269|PubMed:7739542}. |
Tissue Specificity | Highly expressed in testis and placenta. Low levels in bronchial epithelial cells. {ECO:0000269|PubMed:9840943}. |
Top Pathways | Oocyte meiosis, Cell cycle, Measles, Viral carcinogenesis, PI3K-Akt signaling pathway |
cyclin E CRISPR/Cas9 KO Plasmid (h) - sc-400105 from Santa Cruz Biotechnology
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cyclin E HDR Plasmid (h) - sc-400105-HDR from Santa Cruz Biotechnology
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cyclin E Double Nickase Plasmid (h) - sc-400105-NIC from Santa Cruz Biotechnology
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cyclin E Double Nickase Plasmid (h2) - sc-400105-NIC-2 from Santa Cruz Biotechnology
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cyclin E CRISPR Activation Plasmid (h) - sc-400105-ACT from Santa Cruz Biotechnology
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cyclin E CRISPR Activation Plasmid (h2) - sc-400105-ACT-2 from Santa Cruz Biotechnology
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cyclin E Lentiviral Activation Particles (h) - sc-400105-LAC from Santa Cruz Biotechnology
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cyclin E Lentiviral Activation Particles (h2) - sc-400105-LAC-2 from Santa Cruz Biotechnology
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cyclin E siRNA (h) - sc-29288 from Santa Cruz Biotechnology
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cyclin E shRNA Plasmid (h) - sc-29288-SH from Santa Cruz Biotechnology
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cyclin E shRNA (h) Lentiviral Particles - sc-29288-V from Santa Cruz Biotechnology
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Cyclin E1 RNAi - H00000898-R02 from Novus Biologicals
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Cyclin E1 RNAi - H00000898-R01 from Novus Biologicals
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MISSION® esiRNA - EHU070111 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN5635 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND5635 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR04586 from Sigma-Aldrich
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CCNE1 siRNA (Human) - CRH0630 from Cohesion Biosciences
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CCNE1 - MBS8231921 from MyBioSource
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shRNA set against Human CCNE1 (NM_001238.2) - SHH257881 from Creative biogene
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Human CCNE1 siRNA - orb261132 from Biorbyt
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CCNE1 shRNA Plasmid (Human) - CHH0630 from Cohesion Biosciences
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CCNE1 miRNA 3'UTR clone - MiUTR3H-00584 from Creative biogene
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