Gene Symbol |
SEMA3A
|
Entrez Gene |
10371
|
Alt Symbol |
COLL1, HH16, Hsema-I, Hsema-III, SEMA1, SEMAD, SEMAIII, SEMAL, SemD, coll-1
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
|
Other Description |
collapsin 1|semaphorin D|semaphorin III|semaphorin L|semaphorin-3A
|
Swissprots |
Q14563
|
Accessions |
AAC78622 AAP22350 AAS00353 AAS02028 CAD91050 CAI84571 CCF77004 EAL24185 EAW76982 Q14563 AK289954 BAF82643 BC111416 AAI11417 BM723807 BU186364 BX491494 CR748125 DR002146 L26081 AAA65938 XM_005250110 XP_005250167 XM_005250111 XP_005250168 XM_006715839 XP_006715902 XM_011515734 XP_011514036 XM_011515735 XP_011514037 NM_006080 NP_006071
|
Function |
Involved in the development of the olfactory system and in neuronal control of puberty. Induces the collapse and paralysis of neuronal growth cones. Could serve as a ligand that guides specific growth cones by a motility-inhibiting mechanism. Binds to the complex neuropilin-1/plexin-1. {ECO:0000269|PubMed:22416012}.
|
Subcellular Location |
Secreted {ECO:0000250}.
|
Top Pathways |
Axon guidance
|