Gene Symbol | SEMA3A |
---|---|
Entrez Gene | 10371 |
Alt Symbol | COLL1, HH16, Hsema-I, Hsema-III, SEMA1, SEMAD, SEMAIII, SEMAL, SemD, coll-1 |
Species | Human |
Gene Type | protein-coding |
Description | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A |
Other Description | collapsin 1|semaphorin D|semaphorin III|semaphorin L|semaphorin-3A |
Swissprots | Q14563 |
Accessions | AAC78622 AAP22350 AAS00353 AAS02028 CAD91050 CAI84571 CCF77004 EAL24185 EAW76982 Q14563 AK289954 BAF82643 BC111416 AAI11417 BM723807 BU186364 BX491494 CR748125 DR002146 L26081 AAA65938 XM_005250110 XP_005250167 XM_005250111 XP_005250168 XM_006715839 XP_006715902 XM_011515734 XP_011514036 XM_011515735 XP_011514037 NM_006080 NP_006071 |
Function | Involved in the development of the olfactory system and in neuronal control of puberty. Induces the collapse and paralysis of neuronal growth cones. Could serve as a ligand that guides specific growth cones by a motility-inhibiting mechanism. Binds to the complex neuropilin-1/plexin-1. {ECO:0000269|PubMed:22416012}. |
Subcellular Location | Secreted {ECO:0000250}. |
Top Pathways | Axon guidance |
SEMA3A CRISPR/Cas9 KO Plasmid (h) - sc-400716 from Santa Cruz Biotechnology
|
||||||||
SEMA3A HDR Plasmid (h) - sc-400716-HDR from Santa Cruz Biotechnology
|
||||||||
SEMA3A Double Nickase Plasmid (h) - sc-400716-NIC from Santa Cruz Biotechnology
|
||||||||
SEMA3A Double Nickase Plasmid (h2) - sc-400716-NIC-2 from Santa Cruz Biotechnology
|
||||||||
SEMA3A CRISPR Activation Plasmid (h) - sc-400716-ACT from Santa Cruz Biotechnology
|
||||||||
SEMA3A CRISPR Activation Plasmid (h2) - sc-400716-ACT-2 from Santa Cruz Biotechnology
|
||||||||
SEMA3A Lentiviral Activation Particles (h) - sc-400716-LAC from Santa Cruz Biotechnology
|
||||||||
SEMA3A Lentiviral Activation Particles (h2) - sc-400716-LAC-2 from Santa Cruz Biotechnology
|
||||||||
SEMA3A siRNA (h) - sc-36470 from Santa Cruz Biotechnology
|
||||||||
SEMA3A shRNA Plasmid (h) - sc-36470-SH from Santa Cruz Biotechnology
|
||||||||
SEMA3A shRNA (h) Lentiviral Particles - sc-36470-V from Santa Cruz Biotechnology
|
||||||||
Semaphorin 3A RNAi - H00010371-R02 from Novus Biologicals
|
||||||||
MISSION® esiRNA - EHU021581 from Sigma-Aldrich
|
||||||||
CompoZr® Knockout ZFN Kit - CKOZFN19063 from Sigma-Aldrich
|
||||||||
CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND19063 from Sigma-Aldrich
|
||||||||
SEMA3A siRNA (Human) - CRH7028 from Cohesion Biosciences
|
||||||||
SEMA3A - MBS8202829 from MyBioSource
|
||||||||
shRNA set against Human SEMA3A (NM_006080.2) - SHH404184 from Creative biogene
|
||||||||
shRNA set against Human SEMA3A(NM_006080.2) - SHR213412 from Creative biogene
|
||||||||
Human SEMA3A siRNA - orb267530 from Biorbyt
|
||||||||
SEMA3A shRNA Plasmid (Human) - CHH7028 from Cohesion Biosciences
|
||||||||
SEMA3A miRNA 3'UTR clone - MiUTR1H-09248 from Creative biogene
|