| Gene Symbol |
SLAIN2
|
| Entrez Gene |
57606
|
| Alt Symbol |
KIAA1458
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
SLAIN motif family, member 2
|
| Other Description |
SLAIN motif-containing protein 2
|
| Swissprots |
A8K4P1 Q9P270 Q8N5R3
|
| Accessions |
EAW93057 EAW93058 Q9P270 AB040891 BAA95982 AK025264 BAB15095 AK026476 AK291006 BAF83695 BC006139 BC007701 BC012067 BC031691 AAH31691 BC040993 AAH40993 CB157681 Z25182 XM_005248121 XP_005248178 NM_020846 NP_065897
|
| Function |
Binds to the plus end of microtubules and regulates microtubule dynamics and microtubule organization. Promotes cytoplasmic microtubule nucleation and elongation. Required for normal structure of the microtubule cytoskeleton during interphase. {ECO:0000269|PubMed:21646404}.
|
| Subcellular Location |
Cytoplasm, cytoskeleton. Note=Colocalizes with microtubules. Detected at the plus end of growing microtubules.
|
| Tissue Specificity |
Widely expressed with highest levels in adult liver, testis and ovary, and lowest levels in adult pancreas and spleen and in fetal brain. {ECO:0000269|PubMed:10819331}.
|