Gene Symbol | SLAIN2 |
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Entrez Gene | 57606 |
Alt Symbol | KIAA1458 |
Species | Human |
Gene Type | protein-coding |
Description | SLAIN motif family, member 2 |
Other Description | SLAIN motif-containing protein 2 |
Swissprots | A8K4P1 Q9P270 Q8N5R3 |
Accessions | EAW93057 EAW93058 Q9P270 AB040891 BAA95982 AK025264 BAB15095 AK026476 AK291006 BAF83695 BC006139 BC007701 BC012067 BC031691 AAH31691 BC040993 AAH40993 CB157681 Z25182 XM_005248121 XP_005248178 NM_020846 NP_065897 |
Function | Binds to the plus end of microtubules and regulates microtubule dynamics and microtubule organization. Promotes cytoplasmic microtubule nucleation and elongation. Required for normal structure of the microtubule cytoskeleton during interphase. {ECO:0000269|PubMed:21646404}. |
Subcellular Location | Cytoplasm, cytoskeleton. Note=Colocalizes with microtubules. Detected at the plus end of growing microtubules. |
Tissue Specificity | Widely expressed with highest levels in adult liver, testis and ovary, and lowest levels in adult pancreas and spleen and in fetal brain. {ECO:0000269|PubMed:10819331}. |
SLAIN2 CRISPR/Cas9 KO Plasmid (h) - sc-409306 from Santa Cruz Biotechnology
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SLAIN2 HDR Plasmid (h) - sc-409306-HDR from Santa Cruz Biotechnology
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SLAIN2 Double Nickase Plasmid (h) - sc-409306-NIC from Santa Cruz Biotechnology
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SLAIN2 Double Nickase Plasmid (h2) - sc-409306-NIC-2 from Santa Cruz Biotechnology
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SLAIN2 CRISPR Activation Plasmid (h) - sc-409306-ACT from Santa Cruz Biotechnology
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SLAIN2 CRISPR Activation Plasmid (h2) - sc-409306-ACT-2 from Santa Cruz Biotechnology
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SLAIN2 Lentiviral Activation Particles (h) - sc-409306-LAC from Santa Cruz Biotechnology
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SLAIN2 Lentiviral Activation Particles (h2) - sc-409306-LAC-2 from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU046661 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN19389 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND19389 from Sigma-Aldrich
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SLAIN2 siRNA (Human) - CRJ1576 from Cohesion Biosciences
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SLAIN2 - MBS8227712 from MyBioSource
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shRNA set against Human SLAIN2 (NM_020846.1) - SHH408132 from Creative biogene
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Human SLAIN2 siRNA - orb272077 from Biorbyt
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SLAIN2 shRNA Plasmid (Human) - CHJ1576 from Cohesion Biosciences
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SLAIN2 miRNA 3'UTR clone - MiUTR4H-TG08096 from Creative biogene
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