| Gene Symbol | IGFBP3 |
|---|---|
| Entrez Gene | 282261 |
| Alt Symbol | IGFBP-3 |
| Species | Bovine |
| Gene Type | protein-coding |
| Description | insulin-like growth factor binding protein 3 |
| Other Description | IBP-3|IGF-binding protein 3|insulin-like growth factor binding protein-3|insulin-like growth factor-binding protein 3 |
| Swissprots | A6QPI3 P20959 Q9GJV5 |
| Accessions | AAB41430 AAG29825 AAP74968 AAQ55241 AFN44375 DAA30472 P20959 AF305199 AAG29824 BC149336 AAI49337 M76478 AAA30582 XM_010810156 XP_010808458 NM_174556 NP_776981 |
| Function | IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors. Also exhibits IGF-independent antiproliferative and apoptotic effects mediated by its receptor TMEM219/IGFBP-3R. |
| Subcellular Location | Secreted. |
| Tissue Specificity | Plasma; expressed by most tissues. |
| Top Pathways | p53 signaling pathway, Transcriptional misregulation in cancer |
IGFBP3 Antibody - abx104404 from Abbexa
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Insulin Like Growth Factor Binding Protein 3 (IGFBP3), Polyclonal Antibody - MBS2006016 from MyBioSource
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Insulin Like Growth Factor Binding Protein 3 (IGFBP3), Polyclonal Antibody - MBS2013952 from MyBioSource
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Insulin Like Growth Factor Binding Protein 3 (IGFBP3), Polyclonal Antibody - MBS2001418 from MyBioSource
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Insulin Like Growth Factor Binding Protein 3 (IGFBP3), Polyclonal Antibody - MBS2014524 from MyBioSource
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Insulin Like Growth Factor Binding Protein 3 (IGFBP3), Polyclonal Antibody - MBS2005309 from MyBioSource
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Insulin Like Growth Factor Binding Protein 3 (IGFBP3), Polyclonal Antibody - MBS2014044 from MyBioSource
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Insulin Like Growth Factor Binding Protein 3 (IGFBP3), Polyclonal Antibody - MBS2005953 from MyBioSource
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Insulin Like Growth Factor Binding Protein 3 (IGFBP3), Polyclonal Antibody - MBS2002902 from MyBioSource
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Insulin Like Growth Factor Binding Protein 3 (IGFBP3), Polyclonal Antibody - MBS2007003 from MyBioSource
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Anti-IGFBP3 (internal region) polyclonal antibody - CPBT-54427GC from Creative Diagnostics
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Insulin Like Growth Factor Binding Protein 3, Polyclonal Antibody - MBS2026823 from MyBioSource
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Insulin Like Growth Factor Binding Protein 3, Polyclonal Antibody - MBS2032337 from MyBioSource
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