Gene Symbol | IGFBP3 |
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Entrez Gene | 282261 |
Alt Symbol | IGFBP-3 |
Species | Bovine |
Gene Type | protein-coding |
Description | insulin-like growth factor binding protein 3 |
Other Description | IBP-3|IGF-binding protein 3|insulin-like growth factor binding protein-3|insulin-like growth factor-binding protein 3 |
Swissprots | A6QPI3 P20959 Q9GJV5 |
Accessions | AAB41430 AAG29825 AAP74968 AAQ55241 AFN44375 DAA30472 P20959 AF305199 AAG29824 BC149336 AAI49337 M76478 AAA30582 XM_010810156 XP_010808458 NM_174556 NP_776981 |
Function | IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors. Also exhibits IGF-independent antiproliferative and apoptotic effects mediated by its receptor TMEM219/IGFBP-3R. |
Subcellular Location | Secreted. |
Tissue Specificity | Plasma; expressed by most tissues. |
Top Pathways | p53 signaling pathway, Transcriptional misregulation in cancer |
Cow IGFBP3 Protein - abx067249 from Abbexa
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Recombinant Bovine Insulin-like growth factor-binding protein 3(IGFBP3) - CSB-YP011097BO CSB-EP011097BO CSB-BP011097BO CSB-MP011097BO from Cusabio
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IGFBP3 Recombinant Protein (OPCD04189) - OPCD04189 from Aviva Systems Biology
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Insulin Like Growth Factor Binding Protein 3, Recombinant Protein - MBS2031254 from MyBioSource
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Insulin Like Growth Factor Binding Protein 3, Recombinant Protein - MBS2033599 from MyBioSource
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Insulin-Like Growth Factor Binding Protein 3 Human, Recombinant Protein - MBS638095 from MyBioSource
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Insulin-like growth factor-binding protein 3 (IGFBP3), Recombinant Protein - MBS960047 from MyBioSource
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