Gene Symbol |
MAGEE1
|
Entrez Gene |
57692
|
Alt Symbol |
DAMAGE, HCA1
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
melanoma antigen family E1
|
Other Description |
MAGE-E1 antigen|alpha-dystrobrevin-associated MAGE Protein|dystrobrevin-associated MAGE protein|hepatocellular carcinoma-associated HCA1|hepatocellular carcinoma-associated protein 1|melanoma antigen family E, 1|melanoma-associated antigen E1
|
Swissprots |
Q5JXC7 Q9HCI5 Q9H216 Q8TD92 Q86TG0
|
Accessions |
CAI42970 EAW98620 Q9HCI5 AB046807 BAB13413 AF320909 AAG38605 AF490507 AAM08354 AK291270 BAF83959 BC050588 AAH50588 DA411859 NM_020932 NP_065983
|
Function |
May enhance ubiquitin ligase activity of RING-type zinc finger-containing E3 ubiquitin-protein ligases. Proposed to act through recruitment and/or stabilization of the Ubl-conjugating enzyme (E2) at the E3:substrate complex. {ECO:0000269|PubMed:20864041}.
|
Subcellular Location |
Cytoplasm, perinuclear region {ECO:0000250}. Nucleus {ECO:0000250}. Cell membrane {ECO:0000250}. Note=In the skeletal muscle, found at the postsynaptic membrane and is associated with a subset of myonuclei. May reside within nuclei and/or in perinuclear compartments. In peripheral nerves, colocalizes with DTNA in the Schwann cell membrane (By similarity). {ECO:0000250}.
|