Gene Symbol | MAGEE1 |
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Entrez Gene | 57692 |
Alt Symbol | DAMAGE, HCA1 |
Species | Human |
Gene Type | protein-coding |
Description | melanoma antigen family E1 |
Other Description | MAGE-E1 antigen|alpha-dystrobrevin-associated MAGE Protein|dystrobrevin-associated MAGE protein|hepatocellular carcinoma-associated HCA1|hepatocellular carcinoma-associated protein 1|melanoma antigen family E, 1|melanoma-associated antigen E1 |
Swissprots | Q5JXC7 Q9HCI5 Q9H216 Q8TD92 Q86TG0 |
Accessions | CAI42970 EAW98620 Q9HCI5 AB046807 BAB13413 AF320909 AAG38605 AF490507 AAM08354 AK291270 BAF83959 BC050588 AAH50588 DA411859 NM_020932 NP_065983 |
Function | May enhance ubiquitin ligase activity of RING-type zinc finger-containing E3 ubiquitin-protein ligases. Proposed to act through recruitment and/or stabilization of the Ubl-conjugating enzyme (E2) at the E3:substrate complex. {ECO:0000269|PubMed:20864041}. |
Subcellular Location | Cytoplasm, perinuclear region {ECO:0000250}. Nucleus {ECO:0000250}. Cell membrane {ECO:0000250}. Note=In the skeletal muscle, found at the postsynaptic membrane and is associated with a subset of myonuclei. May reside within nuclei and/or in perinuclear compartments. In peripheral nerves, colocalizes with DTNA in the Schwann cell membrane (By similarity). {ECO:0000250}. |
MAGE-E1 CRISPR/Cas9 KO Plasmid (h) - sc-412877 from Santa Cruz Biotechnology
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MAGE-E1 HDR Plasmid (h) - sc-412877-HDR from Santa Cruz Biotechnology
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MAGE-E1 Double Nickase Plasmid (h) - sc-412877-NIC from Santa Cruz Biotechnology
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MAGE-E1 Double Nickase Plasmid (h2) - sc-412877-NIC-2 from Santa Cruz Biotechnology
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MAGE-E1 CRISPR Activation Plasmid (h) - sc-412877-ACT from Santa Cruz Biotechnology
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MAGE-E1 CRISPR Activation Plasmid (h2) - sc-412877-ACT-2 from Santa Cruz Biotechnology
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MAGE-E1 Lentiviral Activation Particles (h) - sc-412877-LAC from Santa Cruz Biotechnology
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MAGE-E1 Lentiviral Activation Particles (h2) - sc-412877-LAC-2 from Santa Cruz Biotechnology
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MAGE-E1 siRNA (h) - sc-75736 from Santa Cruz Biotechnology
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MAGE-E1 shRNA Plasmid (h) - sc-75736-SH from Santa Cruz Biotechnology
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MAGE-E1 shRNA (h) Lentiviral Particles - sc-75736-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU101961 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN12935 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND12935 from Sigma-Aldrich
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MAGEE1 siRNA (Human) - CRJ1636 from Cohesion Biosciences
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shRNA set against Human MAGEE1 (NM_020932.2) - SHH336951 from Creative biogene
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MAGEE1 shRNA Plasmid (Human) - CHJ1636 from Cohesion Biosciences
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MAGEE1 miRNA 3'UTR clone - MiUTR3H-02928 from Creative biogene
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