IMPA1

Gene Symbol IMPA1
Entrez Gene 3612
Alt Symbol IMP, IMPA
Species Human
Gene Type protein-coding
Description inositol(myo)-1(or 4)-monophosphatase 1
Other Description D-galactose 1-phosphate phosphatase|IMP 1|IMPase 1|inositol monophosphatase 1|inositol-1(or 4)-monophosphatase 1|lithium-sensitive myo-inositol monophosphatase A1
Swissprots Q9UK71 P29218 J3KQT7 B7Z6Q4 B2R733 B4DLN3
Accessions AAD52997 CAA72195 EAW87095 EAW87096 EAW87097 EAW87098 EAW87099 EAW87100 P29218 AF042729 AAB97468 AI921211 AK297078 BAG59595 AK300750 BAH13340 AK312823 BAG35680 BC008381 AAH08381 BC009565 AAH09565 BP270804 DB299262 DC375686 HQ447127 ADQ31614 X66922 CAA47359 NM_001144878 NP_001138350 NM_001144879 NP_001138351 NM_005536 NP_005527
Function Responsible for the provision of inositol required for synthesis of phosphatidylinositol and polyphosphoinositides and has been implicated as the pharmacological target for lithium action in brain. Has broad substrate specificity and can use myo- inositol monophosphates, myo-inositol 1,3-diphosphate, myo- inositol 1,4-diphosphate, scyllo-inositol-phosphate, D-galactose 1-phosphate, glucose-1-phosphate, glucose-6-phosphate, fructose-1- phosphate, beta-glycerophosphate, and 2'-AMP as substrates. {ECO:0000269|PubMed:17068342, ECO:0000269|PubMed:8718889, ECO:0000269|PubMed:9462881}.
Subcellular Location Cytoplasm {ECO:0000269|PubMed:17068342}.
Top Pathways Inositol phosphate metabolism, Phosphatidylinositol signaling system

IMPA1-Over-expression-Lysate - LY10769a from Abgent, a WuXi AppTec company

Category Cell Lysate
Prices $325.00
Sizes 100 µg
Western blot analysis of his-tag IMPA1 (arrow) using his tag antibody. 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the IMPA1 gene

IMPA1 293T Cell Transient Overexpression Lysate(Denatured) - H00003612-T01 from Acris Antibodies

Category Cell Lysate
Prices $320.00
Sizes 100 µl

IMPA1 overexpression lysate - LY428539 from Acris Antibodies

Category Cell Lysate
Prices $280.00
Sizes 100 µg

IMPA1 293 Cell Lysate - 408059 from ABBIOTEC

Category Cell Lysate
Prices $392.00
Sizes 100 µg

IMPA1 Overexpression Lysate (Denatured) - H00003612-T01 from Novus Biologicals

Category Cell Lysate
Prices $279.00
Sizes 100 µl
IMPA1 transfected lysate.

IMPA1 Overexpression Lysate (Native) - NBL1-11982 from Novus Biologicals

Category Cell Lysate
Prices $329.00
Sizes 100 µg

IMPA1 Over-expression Lysate Product - GWB-B6189E from Genway Biotech

Category Cell Lysate
Prices $346.00
Sizes 100 µg
Species Human

Panoply™ Human IMPA1 Knockdown Stable Cell Line - CSC-DC007629 from Creative biogene

Category Cell Line
Species Human
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