SLC24A1

Gene Symbol SLC24A1
Entrez Gene 9187
Alt Symbol CSNB1D, HsT17412, NCKX, NCKX1, RODX
Species Human
Gene Type protein-coding
Description solute carrier family 24 (sodium/potassium/calcium exchanger), member 1
Other Description Na(+)/K(+)/Ca(2+)-exchange protein 1|retinal rod Na+/Ca+/K+ exchanger|sodium/potassium/calcium exchanger 1|solute carrier family 24 member 1
Swissprots O75184 Q17RM9 O43485 O60721
Accessions EAW77739 EAW77740 EAW77741 O60721 AB014602 BAA31677 AF026132 AAB97832 AF062921 AAC16732 AF062922 AAC77912 AI026072 AK300633 BAG62323 AK304006 BAG64922 BC012630 BC029407 BC117263 AAI17264 BC143375 AAI43376 BM129630 BM681488 EL947516 EL948740 XM_005254778 XP_005254835 XM_005254781 XP_005254838 XM_006720764 XP_006720827 XM_006720767 XP_006720830 XM_006720768 XP_006720831 XM_006720769 XP_006720832 XM_011522219 XP_011520521 XM_011522220 XP_011520522 XM_011522221 XP_011520523 XM_011522222 XP_011520524 XM_011522223 XP_011520525 XM_011522225 XP_011520527 XM_011522226 XP_011520528 NM_001254740 NP_001241669 NM_001301031 NP_001287960 NM_001301032 NP_001287961 NM_001301033 NP_001287962 NM_004727 NP_004718
Function Critical component of the visual transduction cascade, controlling the calcium concentration of outer segments during light and darkness. Light causes a rapid lowering of cytosolic free calcium in the outer segment of both retinal rod and cone photoreceptors and the light-induced lowering of calcium is caused by extrusion via this protein which plays a key role in the process of light adaptation. Transports 1 Ca(2+) and 1 K(+) in exchange for 4 Na(+). {ECO:0000269|PubMed:10608890}.
Subcellular Location Membrane; Multi-pass membrane protein.
Tissue Specificity Expressed in the retina, particularly in the inner segment, outer and inner nuclear layers, and ganglion cell layer. {ECO:0000269|PubMed:20850105}.
Top Pathways Phototransduction

NCKX1 (E-6) - sc-393400 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
NCKX1 (E-6): sc-393400. Western blot analysis of NCKX1 expression in human platelet extract (A), Y79 (B), ARPE-19 (C) and MEG-01 (D) whole cell lysates and mouse eye (E) and rat eye (F) tissue extracts.

NCKX1 (E-18) - sc-48892 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
NCKX1 (E-18): sc-48892. Western blot analysis of NCKX1 expression in SK-N-SH whole cell lysate.

NCKX1 (H-300) - sc-98904 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal

NCKX1 (N-13) - sc-48893 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-SLC24A1 antibody - ab127715 from Abcam

Prices $370.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal
Anti-SLC24A1 antibody (ab127715) at 1/5000 dilution + SK N SH whole cell lysate at 30 µg

Anti-SLC24A1 antibody - ab136983 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-SLC24A1 antibody (ab136983) at 1/500 dilution + HepG2 cell lysate at 30 µg

Anti-SLC24A1 antibody - ab84685 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-SLC24A1 antibody (ab84685) at 1 µg/ml (in 5% skim milk / PBS buffer) + Human fetal brain lysate at 10 µgSecondaryHRP conjugated anti-Rabbit IgG at 1/50000 dilution

Anti-SLC24A1 / NCKX Antibody (aa154-203) - LS-C291407 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-SLC24A1 / NCKX Antibody (aa198-243) - LS-C313844 from LifeSpan Bioscience

Prices $345.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-SLC24A1 / NCKX Antibody (aa139-188) - LS-C200678 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of the lysates from HepG2 cells using SLC24A1 antibody.

Anti-SLC24A1 / NCKX Antibody (aa612-661) IHC-plus™ - LS-B9700 from LifeSpan Bioscience

Prices $450.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-SLC24A1 / NCKX antibody IHC staining of human tonsil. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B9700 concentration 10 ug/ml.

SLC24A1 Antibody - NBP1-62521 from Novus Biologicals

Prices $139.00, $329.00
Sizes 20 µl, 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: SLC24A1 Antibody [NBP1-62521] - Titration: 0.2-1 ug/ml, Positive Control: Human brain.

SLC24A1 Antibody - NBP1-92397 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemistry-Paraffin: SLC24A1 Antibody [NBP1-92397] - Staining of human retina shows moderate cytoplasmic positivity in photoreceptors and nerve fibers.

SLC24A1 Antibody - NBP2-20384 from Novus Biologicals

Prices $349.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: SLC24A1 Antibody [NBP2-20384] - Sample (30 ug of whole cell lysate) A: SK-N-SH 5% SDS PAGE gel, diluted at 1:5000.

SLC24A1 Antibody - H00009187-A01 from Novus Biologicals

Prices $269.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal

Anti-SLC24A1 antibody produced in rabbit - HPA039370 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-SLC24A1: <B>Cat. No. HPA039370</B>: Immunohistochemical staining of human placenta shows strong cytoplasmic positivity in trophoblastic cells.

Anti-SLC24A1 antibody produced in rabbit - SAB2701387 from Sigma-Aldrich

Prices $326.50
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-SLC24A1: <B>Cat. No. SAB2701387</B>: Western Blot analysis of SLC24A1 in extracts from <B>Lanes</B><BR/>A. SK-N-SH using <B>Cat. No. SAB2701387</B> at a 1:5000 dilution.

Anti-SLC24A1 antibody produced in rabbit - SAB2102180 from Sigma-Aldrich

Prices $347.50
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-SLC24A1: <B>Cat. No.SAB2102180</B>: SLC24A1 in Fetal Brain tissue lysate with SLC24A1 antibody at 1.0 μg/mL.

SLC24A1 antibody - middle region (ARP43884_P050) - ARP43884_P050 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

SLC24A1 Antibody (OAAF04315) - OAAF04315 from Aviva Systems Biology

Prices $289.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

SLC24A1 Antibody (OAAF07124) - OAAF07124 from Aviva Systems Biology

Prices $289.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

SLC24A1 antibody - orb126363 from Biorbyt

Prices $85.00, $255.00, $425.00
Sizes 25 μg (Trial Size), 100 μg, 200 μg
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts from RAW264.7 cells and K562 cells using SLC24A1 antibody

SLC24A1 antibody - 70R-7367 from Fitzgerald

Prices $345.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal

NCKX1 Antibody - abx008442 from Abbexa

Host Rabbit
Clonality Polyclonal

SLC24A1 Antibody - abx119617 from Abbexa

Host Rabbit
Clonality Polyclonal
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