Gene Symbol |
UQCRC2
|
Entrez Gene |
7385
|
Alt Symbol |
MC3DN5, QCR2, UQCR2
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
ubiquinol-cytochrome c reductase core protein II
|
Other Description |
complex III subunit 2|core protein II|cytochrome b-c1 complex subunit 2, mitochondrial|ubiquinol-cytochrome-c reductase complex core protein 2
|
Swissprots |
Q9BQ05 B3KSN4 P22695
|
Accessions |
EAW50590 EAW50591 EAW50592 P22695 AK093106 AK094006 BAG52796 AK307535 BC000484 AAH00484 BC003136 AAH03136 DQ891390 ABM82316 DQ894565 ABM85491 J04973 AAA35710 NM_003366 NP_003357
|
Function |
This is a component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is part of the mitochondrial respiratory chain. The core protein 2 is required for the assembly of the complex.
|
Subcellular Location |
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
|
Top Pathways |
Alzheimer's disease, Huntington's disease, Cardiac muscle contraction, Non-alcoholic fatty liver disease (NAFLD), Oxidative phosphorylation
|