Gene Symbol | UQCRC2 |
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Entrez Gene | 7385 |
Alt Symbol | MC3DN5, QCR2, UQCR2 |
Species | Human |
Gene Type | protein-coding |
Description | ubiquinol-cytochrome c reductase core protein II |
Other Description | complex III subunit 2|core protein II|cytochrome b-c1 complex subunit 2, mitochondrial|ubiquinol-cytochrome-c reductase complex core protein 2 |
Swissprots | Q9BQ05 B3KSN4 P22695 |
Accessions | EAW50590 EAW50591 EAW50592 P22695 AK093106 AK094006 BAG52796 AK307535 BC000484 AAH00484 BC003136 AAH03136 DQ891390 ABM82316 DQ894565 ABM85491 J04973 AAA35710 NM_003366 NP_003357 |
Function | This is a component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is part of the mitochondrial respiratory chain. The core protein 2 is required for the assembly of the complex. |
Subcellular Location | Mitochondrion inner membrane; Peripheral membrane protein; Matrix side. |
Top Pathways | Alzheimer's disease, Huntington's disease, Cardiac muscle contraction, Non-alcoholic fatty liver disease (NAFLD), Oxidative phosphorylation |
UQCRC2 CRISPR/Cas9 KO Plasmid (h) - sc-406074 from Santa Cruz Biotechnology
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UQCRC2 HDR Plasmid (h) - sc-406074-HDR from Santa Cruz Biotechnology
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UQCRC2 Double Nickase Plasmid (h) - sc-406074-NIC from Santa Cruz Biotechnology
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UQCRC2 Double Nickase Plasmid (h2) - sc-406074-NIC-2 from Santa Cruz Biotechnology
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UQCRC2 CRISPR Activation Plasmid (h) - sc-406074-ACT from Santa Cruz Biotechnology
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UQCRC2 CRISPR Activation Plasmid (h2) - sc-406074-ACT-2 from Santa Cruz Biotechnology
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UQCRC2 Lentiviral Activation Particles (h) - sc-406074-LAC from Santa Cruz Biotechnology
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UQCRC2 Lentiviral Activation Particles (h2) - sc-406074-LAC-2 from Santa Cruz Biotechnology
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UQCRC2 siRNA (h) - sc-72021 from Santa Cruz Biotechnology
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UQCRC2 shRNA Plasmid (h) - sc-72021-SH from Santa Cruz Biotechnology
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UQCRC2 shRNA (h) Lentiviral Particles - sc-72021-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU027211 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN22534 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND22534 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR01184 from Sigma-Aldrich
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UQCRC2 siRNA (Human) - CRH5052 from Cohesion Biosciences
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UQCRC2 RNAi - H00007385-R01 from Novus Biologicals
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UQCRC2 - MBS8209483 from MyBioSource
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shRNA set against Human UQCRC2 (NM_003366.2) - SHH440948 from Creative biogene
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shRNA set against Human UQCRC2(NM_003366.2) - SHL116090 from Creative biogene
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UQCRC2 shRNA Plasmid (Human) - CHH5052 from Cohesion Biosciences
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UQCRC2 miRNA 3'UTR clone - MiUTR1H-11032 from Creative biogene
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