Gene Symbol | USB1 |
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Entrez Gene | 79650 |
Alt Symbol | C16orf57, HVSL1, Mpn1, PN, hUsb1 |
Species | Human |
Gene Type | protein-coding |
Description | U6 snRNA biogenesis 1 |
Other Description | HVSL motif containing 1|U six biogenesis 1|U6 snRNA phosphodiesterase|UPF0406 protein C16orf57|mutated in poikiloderma with neutropenia protein 1|putative U6 snRNA phosphodiesterase |
Swissprots | B4DZW5 B4DWE3 Q96FZ9 Q9H8X8 Q9BQ65 |
Accessions | EAW82962 EAW82963 EAW82964 Q9BQ65 AK023216 BAB14469 AK124443 AK126223 AK293220 BAG56759 AK298473 BAG60684 AK301494 BAG63005 AK303121 BAG64227 BC004415 AAH04415 BC006291 AAH06291 BC007774 AAH07774 BC010099 AAH10099 BC021554 AAH21554 BF733890 BI910866 BM193105 BQ223186 BX117268 DB364698 DB382938 DC363309 DC380401 JF432668 ADZ15885 XM_005256144 XP_005256201 XM_011523328 XP_011521630 XM_011523329 XP_011521631 XM_011523330 XP_011521632 XR_933427 XR_933428 NM_001195302 NP_001182231 NM_001204911 NP_001191840 NM_024598 NP_078874 |
Function | Phosphodiesterase responsible for the U6 snRNA 3' end processing. Acts as an exoribonuclease (RNase) responsible for trimming the poly(U) tract of the last nucleotides in the pre-U6 snRNA molecule, leading to the formation of mature U6 snRNA 3' end-terminated with a 2',3'-cyclic phosphate. {ECO:0000255|HAMAP- Rule:MF_03040, ECO:0000269|PubMed:22899009, ECO:0000269|PubMed:23190533}. |
Subcellular Location | Nucleus {ECO:0000255|HAMAP-Rule:MF_03040, ECO:0000269|PubMed:22899009}. |
USB1 Antibody Blocking Peptide - LS-E27805 from LifeSpan Bioscience
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USB1 Antibody Blocking Peptide - LS-E22784 from LifeSpan Bioscience
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C16orf57 Peptide - AC21-2616-P from Abcore
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C16orf57 Peptide - 42-933P from ProSci
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C16orf57 fusion protein - Ag15689 from Proteintech Group
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Recombinant Human C16orf57, GST-tagged - C16orf57-10410H from Creative Biomart
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C16orf57 - TP302591 from Acris Antibodies
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C16orf57, Peptide - MBS427667 from MyBioSource
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HVSL1 Protein - NBP1-82268PEP from Novus Biologicals
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USB1 Peptide, Human - M34GP17137H from Creative Peptides
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HVSL1 Recombinant Protein Antigen - NBP2-56102PEP from Novus Biologicals
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C16orf57 Immunizing peptide - orb66285 from Biorbyt
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