FDPS
| Gene Symbol | FDPS |
|---|---|
| Entrez Gene | 2224 |
| Alt Symbol | FPPS, FPS |
| Species | Human |
| Gene Type | protein-coding |
| Description | farnesyl diphosphate synthase |
| Other Description | (2E,6E)-farnesyl diphosphate synthase|FPP synthase|FPP synthetase|dimethylallyltranstransferase|farnesyl pyrophosphate synthase|farnesyl pyrophosphate synthetase, dimethylallyltranstransferase, geranyltranstransferase|geranyltranstransferase |
| Swissprots | D3DV91 P14324 Q96G29 E9PCI9 |
| Accessions | CCQ43162 EAW53075 EAW53076 EAW53077 EAW53078 P14324 AK021828 AK022841 BAG51125 AK291084 BAF83773 BC010004 AAH10004 BE047993 BP370037 CD675633 CN346026 D14697 BAA03523 DA610405 DQ893471 ABM84397 DQ895943 ABM86869 J05262 AAA52423 M29863 AAA35820 XM_005244962 XP_005245019 XM_005244963 XP_005245020 NM_001135821 NP_001129293 NM_001135822 NP_001129294 NM_001242824 NP_001229753 NM_001242825 NP_001229754 NM_002004 NP_001995 |
| Function | Key enzyme in isoprenoid biosynthesis which catalyzes the formation of farnesyl diphosphate (FPP), a precursor for several classes of essential metabolites including sterols, dolichols, carotenoids, and ubiquinones. FPP also serves as substrate for protein farnesylation and geranylgeranylation. Catalyzes the sequential condensation of isopentenyl pyrophosphate with the allylic pyrophosphates, dimethylallyl pyrophosphate, and then with the resultant geranylpyrophosphate to the ultimate product farnesyl pyrophosphate. |
| Subcellular Location | Cytoplasm. |
| Top Pathways | Terpenoid backbone biosynthesis, HTLV-I infection, Influenza A |
FDPS (E-15) - sc-70061 from Santa Cruz Biotechnology
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Anti-FDPS antibody - ab38854 from Abcam
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Anti-FDPS antibody - ab89023 from Abcam
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Anti-FDPS antibody - ab123548 from Abcam
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Anti-FDPS antibody [EPR4628] - ab109007 from Abcam
![All lanes : Anti-FDPS antibody [EPR4628] (ab109007) at 1/1000 dilutionLane 1 : THP1 cell lysatesLane 2 : HepG2 cell lysatesLane 3 : Human fetal liver lysates](http://www.bioprodhub.com/system/product_images/ab_products/2/sub_2/18358_FDPS-Primary-antibodies-ab109007-3.jpg)
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Anti-FDPS Antibody (aa54-82, AP) - LS-C214175 from LifeSpan Bioscience
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Anti-FDPS Antibody (aa54-82, APC) - LS-C214176 from LifeSpan Bioscience
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Anti-FDPS Antibody (aa54-82, Biotin) - LS-C214177 from LifeSpan Bioscience
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Anti-FDPS Antibody (aa197-246) - LS-C151404 from LifeSpan Bioscience
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Anti-FDPS Antibody (aa54-82, FITC) - LS-C214178 from LifeSpan Bioscience
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Anti-FDPS Antibody (aa54-82, Azide-free, HRP) - LS-C214179 from LifeSpan Bioscience
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Anti-FDPS Antibody (aa54-82, PE) - LS-C214180 from LifeSpan Bioscience
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Anti-FDPS Antibody (Internal, APC) - LS-C219273 from LifeSpan Bioscience
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Anti-FDPS Antibody (Internal, AP) - LS-C219274 from LifeSpan Bioscience
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Anti-FDPS Antibody (clone 3A6) - LS-C197208 from LifeSpan Bioscience
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Anti-FDPS Antibody (Internal, Biotin) - LS-C219275 from LifeSpan Bioscience
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Anti-FDPS Antibody (Internal, FITC) - LS-C219276 from LifeSpan Bioscience
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Anti-FDPS Antibody (Internal, Azide-free, HRP) - LS-C219277 from LifeSpan Bioscience
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Anti-FDPS Antibody - LS-C307517 from LifeSpan Bioscience
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Anti-FDPS Antibody (Internal, PE) - LS-C219278 from LifeSpan Bioscience
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Anti-FDPS Antibody - LS-C310352 from LifeSpan Bioscience
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Anti-FDPS Antibody - LS-C310353 from LifeSpan Bioscience
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Anti-FDPS Antibody (aa53-82) - LS-C321351 from LifeSpan Bioscience
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Anti-FDPS Antibody - LS-C341843 from LifeSpan Bioscience
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Anti-FDPS Antibody (Internal) - LS-C327371 from LifeSpan Bioscience
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