| Gene Symbol |
KPTN
|
| Entrez Gene |
11133
|
| Alt Symbol |
2E4, MRT41
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
kaptin (actin binding protein)
|
| Other Description |
actin-associated protein 2E4|kaptin
|
| Swissprots |
B3KN86 B4DQ76 Q96GT1 Q9Y664
|
| Accessions |
AAF98790 EAW57487 Q9Y664 AF105369 AAD39358 AK023996 BAG51248 AK225419 AK298672 BAG60838 BC009249 AAH09249 BG388698 DA129265 DA824599 DR759729 XM_011526398 XP_011524700 XM_011526399 XP_011524701 XM_011526400 XP_011524702 XM_011526401 XP_011524703 NM_001291296 NP_001278225 NM_007059 NP_008990 NR_111923
|
| Function |
Necessary for normal neuromorphogenesis. May be involved in actin dynamics. May play a role in producing the sensory apparatus in hair cells. May play a role in actin rearrangements that accompany platelet activation and stereocilia formation. {ECO:0000269|PubMed:10099934, ECO:0000269|PubMed:1372044, ECO:0000269|PubMed:24239382}.
|
| Subcellular Location |
Cytoplasm. Cytoplasm, perinuclear region. Cell projection, stereocilium. Cell projection, growth cone. Note=Perinuclear at the tips of stereocilium in the inner ear. Localized at sites of actin polymerization in motile fibroblasts and neuronal growth cones.
|