RNF38
| Gene Symbol | RNF38 |
|---|---|
| Entrez Gene | 152006 |
| Alt Symbol | - |
| Species | Human |
| Gene Type | protein-coding |
| Description | ring finger protein 38 |
| Other Description | E3 ubiquitin-protein ligase RNF38 |
| Swissprots | B3KSG4 Q9H0F5 B1AM81 Q9H748 Q7LB33 Q8N0Y0 B1AM82 E7EVL3 A6PVP9 |
| Accessions | EAW58305 Q9H0F5 AF394047 AAM73697 AK024996 BAB15050 AK025466 AK093480 BAG52726 AK097653 AL120640 AL136817 CAB66751 AM392682 CAL37560 AV690059 AX748155 BC033786 AAH33786 BG722531 BI459742 BI520161 BU731024 DA189510 DA483270 DQ895235 ABM86161 EU176239 ABW03690 XM_005251366 XP_005251423 XM_005251367 XP_005251424 XM_005251368 XP_005251425 XM_006716721 XP_006716784 XM_011517712 XP_011516014 XM_011517713 XP_011516015 NM_022781 NP_073618 NM_194328 NP_919309 NM_194329 NP_919310 NM_194330 NP_919311 NM_194332 NP_919313 NM_194331 |
| Function | Acts as an E3 ubiquitin-protein ligase able to ubiquitinate p53/TP53 which promotes its relocalization to discrete foci associated with PML nuclear bodies. Exhibits preference for UBE2D2 as a E2 enzyme. {ECO:0000269|PubMed:23973461}. |
| Subcellular Location | Nucleus {ECO:0000269|PubMed:23973461}. |
| Tissue Specificity | Widely expressed with highest levels in testis. {ECO:0000269|PubMed:12074600}. |
RNF38 CRISPR/Cas9 KO Plasmid (h) - sc-408329 from Santa Cruz Biotechnology
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RNF38 HDR Plasmid (h) - sc-408329-HDR from Santa Cruz Biotechnology
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RNF38 Double Nickase Plasmid (h) - sc-408329-NIC from Santa Cruz Biotechnology
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RNF38 Double Nickase Plasmid (h2) - sc-408329-NIC-2 from Santa Cruz Biotechnology
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RNF38 CRISPR Activation Plasmid (h) - sc-408329-ACT from Santa Cruz Biotechnology
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RNF38 CRISPR Activation Plasmid (h2) - sc-408329-ACT-2 from Santa Cruz Biotechnology
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RNF38 Lentiviral Activation Particles (h) - sc-408329-LAC from Santa Cruz Biotechnology
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RNF38 Lentiviral Activation Particles (h2) - sc-408329-LAC-2 from Santa Cruz Biotechnology
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RNF38 siRNA (h) - sc-92932 from Santa Cruz Biotechnology
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RNF38 shRNA Plasmid (h) - sc-92932-SH from Santa Cruz Biotechnology
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RNF38 shRNA (h) Lentiviral Particles - sc-92932-V from Santa Cruz Biotechnology
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RNF38 RNAi - H00152006-R06 from Novus Biologicals
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RNF38 RNAi - H00152006-R03 from Novus Biologicals
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RNF38 RNAi - H00152006-R04 from Novus Biologicals
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RNF38 RNAi - H00152006-R05 from Novus Biologicals
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MISSION® esiRNA - EHU083681 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN18433 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND18433 from Sigma-Aldrich
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RNF38 siRNA (Human) - CRJ5722 from Cohesion Biosciences
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RNF38 RNAi - H00152006-R02 from Novus Biologicals
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RNF38 RNAi - H00152006-R01 from Novus Biologicals
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RNF38 - MBS8207051 from MyBioSource
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shRNA set against Human RNF38 (NM_194332.2) - SHH397312 from Creative biogene
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shRNA set against Human RNF38(NM_194329.2) - SHR186916 from Creative biogene
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shRNA set against Human RNF38(NM_194328.2) - SHR186996 from Creative biogene
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