Gene Symbol | CX3CR1 |
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Entrez Gene | 1524 |
Alt Symbol | CCRL1, CMKBRL1, CMKDR1, GPR13, GPRV28, V28 |
Species | Human |
Gene Type | protein-coding |
Description | chemokine (C-X3-C motif) receptor 1 |
Other Description | C-X3-C CKR-1|CMK-BRL-1|CMK-BRL1|CX3C chemokine receptor 1|G protein-coupled receptor 13|G-protein coupled receptor 13|beta chemokine receptor-like 1|chemokine (C-C) receptor-like 1|chemokine (C-X3-C) receptor 1|fractalkine receptor |
Swissprots | P49238 J3KP17 B2R5Z4 A0N0N6 |
Accessions | AAK08627 ABK41927 ABS29268 EAW64575 EAW64576 P49238 AI400350 AK225764 AK307911 AK312373 BAG35291 BC017855 BC028078 AAH28078 BG541473 DA396634 DA406242 DB274136 DQ891063 ABM81989 DQ894243 ABM85169 U20350 AAA91783 U28934 AAA87032 NM_001171171 NP_001164642 NM_001171172 NP_001164643 NM_001171174 NP_001164645 NM_001337 NP_001328 |
Function | Receptor for the CX3C chemokine fractalkine and mediates both its adhesive and migratory functions. Acts as coreceptor with CD4 for HIV-1 virus envelope protein (in vitro). Isoform 2 and isoform 3 seem to be more potent HIV-1 coreceptors than isoform 1. |
Subcellular Location | Cell membrane; Multi-pass membrane protein. |
Tissue Specificity | Expressed in lymphoid and neural tissues. |
Top Pathways | Cytokine-cytokine receptor interaction, Chemokine signaling pathway |
CX3CR1 peptide - ab8124 from Abcam
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CX3CR1 peptide - ab8125 from Abcam
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Human CX3CR1 full length protein - ab112276 from Abcam
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Human CX3CR1 full length protein - ab152311 from Abcam
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Human CX3CR1 peptide - ab64633 from Abcam
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Human CX3CR1 peptide - ab101834 from Abcam
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Human CX3CR1 protein fragment - ab152312 from Abcam
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ACKR4 / CCRL1 / CCR11 Antibody Blocking Peptide - LS-E22678 from LifeSpan Bioscience
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ACKR4 / CCRL1 / CCR11 Antibody Blocking Peptide - LS-E22679 from LifeSpan Bioscience
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ACKR4 / CCRL1 / CCR11 Antibody Blocking Peptide - LS-E28281 from LifeSpan Bioscience
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ACKR4 / CCRL1 / CCR11 Antibody Blocking Peptide - LS-E28282 from LifeSpan Bioscience
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CX3CR1 Antibody Blocking Peptide - LS-E29444 from LifeSpan Bioscience
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CX3CR1 Antibody Blocking Peptide - LS-E29885 from LifeSpan Bioscience
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CX3CR1 Antibody Blocking Peptide - LS-E29911 from LifeSpan Bioscience
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Recombinant Human CCR11 Protein - H00051554-P01 from Novus Biologicals
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Recombinant Human CX3CR1 Protein - H00001524-Q01 from Novus Biologicals
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Recombinant Human CX3CR1 Protein - H00001524-P02 from Novus Biologicals
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Recombinant Human CX3CR1 Protein - H00001524-P01 from Novus Biologicals
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CX3CR1 Blocking Peptide - NBP1-76949PEP from Novus Biologicals
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CX3CR1 Blocking Peptide - NBP1-76872PEP from Novus Biologicals
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CX3CR1-Antibody-N-term-Blocking-Peptide - BP17011a from Abgent, a WuXi AppTec company
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CX3CR1 peptide - GTX28124 from GeneTex
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CX3CR1 Protein Lysate (APL10189) - APL10189 from Aviva Systems Biology
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CX3CR1 Protein Lysate (APL10190) - APL10190 from Aviva Systems Biology
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CCRL1 Blocking Peptide - 33R-10400 from Fitzgerald
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