CX3CR1

Gene Symbol	CX3CR1
Entrez Gene	1524
Alt Symbol	CCRL1, CMKBRL1, CMKDR1, GPR13, GPRV28, V28
Species	Human
Gene Type	protein-coding
Description	chemokine (C-X3-C motif) receptor 1
Other Description	C-X3-C CKR-1|CMK-BRL-1|CMK-BRL1|CX3C chemokine receptor 1|G protein-coupled receptor 13|G-protein coupled receptor 13|beta chemokine receptor-like 1|chemokine (C-C) receptor-like 1|chemokine (C-X3-C) receptor 1|fractalkine receptor
Swissprots	P49238 J3KP17 B2R5Z4 A0N0N6
Accessions	AAK08627 ABK41927 ABS29268 EAW64575 EAW64576 P49238 AI400350 AK225764 AK307911 AK312373 BAG35291 BC017855 BC028078 AAH28078 BG541473 DA396634 DA406242 DB274136 DQ891063 ABM81989 DQ894243 ABM85169 U20350 AAA91783 U28934 AAA87032 NM_001171171 NP_001164642 NM_001171172 NP_001164643 NM_001171174 NP_001164645 NM_001337 NP_001328
Function	Receptor for the CX3C chemokine fractalkine and mediates both its adhesive and migratory functions. Acts as coreceptor with CD4 for HIV-1 virus envelope protein (in vitro). Isoform 2 and isoform 3 seem to be more potent HIV-1 coreceptors than isoform 1.
Subcellular Location	Cell membrane; Multi-pass membrane protein.
Tissue Specificity	Expressed in lymphoid and neural tissues.
Top Pathways	Cytokine-cytokine receptor interaction, Chemokine signaling pathway

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

CX3CR1 CRISPR/Cas9 KO Plasmid (h) - sc-401206 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

CX3CR1 HDR Plasmid (h) - sc-401206-HDR from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

CX3CR1 Double Nickase Plasmid (h) - sc-401206-NIC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

CX3CR1 Double Nickase Plasmid (h2) - sc-401206-NIC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

CX3CR1 CRISPR Activation Plasmid (h) - sc-401206-ACT from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

CX3CR1 CRISPR Activation Plasmid (h2) - sc-401206-ACT-2 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

CX3CR1 Lentiviral Activation Particles (h) - sc-401206-LAC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

CX3CR1 Lentiviral Activation Particles (h2) - sc-401206-LAC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

CX3CR1 siRNA (h) - sc-39904 from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

CX3CR1 shRNA Plasmid (h) - sc-39904-SH from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

CX3CR1 shRNA (h) Lentiviral Particles - sc-39904-V from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

CCR11 RNAi - H00051554-R04 from Novus Biologicals Category siRNA Prices $399.00 Sizes 20 nmol Species Reactivities Human

CX3CR1 RNAi - H00001524-R02 from Novus Biologicals Category siRNA Prices $409.00 Sizes 20 nmol Species Reactivities Human

MISSION® esiRNA - EHU140721 from Sigma-Aldrich Category siRNA Prices $140.00, $250.00 Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN1947 from Sigma-Aldrich Category ZFN Kit Prices $4,999.00 Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND1947 from Sigma-Aldrich Category ZFN Kit Prices $3,999.00 Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR10791 from Sigma-Aldrich Category miRNA

CX3CR1 siRNA (Human) - CRH1079 from Cohesion Biosciences Category siRNA Prices $340.00, $510.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

CX3CR1 - MBS8206571 from MyBioSource Prices $365.00, $515.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

shRNA set against Human CX3CR1 (NM_001337.3) - SHH272077 from Creative biogene Category siRNA Species Reactivities Human

shRNA set against Human CX3CR1(NM_001337.3) - SHG153883 from Creative biogene Category siRNA Species Reactivities Human

Human CX3CR1 siRNA - orb261581 from Biorbyt Category siRNA Prices $485.00, $629.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

CX3CR1 shRNA Plasmid (Human) - CHH1079 from Cohesion Biosciences Category siRNA Prices $500.00, $750.00 Sizes 150 µg, 300 µg Species Reactivities Human

CX3CR1 miRNA 3'UTR clone - MiUTR1H-02569 from Creative biogene Species Reactivities Human

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